OATPs, OATs and OCTs: the organic anion and cation transporters of the SLCO and SLC22A gene superfamilies
M Roth, A Obaidat, B Hagenbuch - British journal of …, 2012 - Wiley Online Library
The human organic anion and cation transporters are classified within two SLC
superfamilies. Superfamily SLCO (formerly SLC21A) consists of organic anion transporting …
superfamilies. Superfamily SLCO (formerly SLC21A) consists of organic anion transporting …
The biochemistry and medical significance of the flavonoids
BH Havsteen - Pharmacology & therapeutics, 2002 - Elsevier
Flavonoids are plant pigments that are synthesised from phenylalanine, generally display
marvelous colors known from flower petals, mostly emit brilliant fluorescence when they are …
marvelous colors known from flower petals, mostly emit brilliant fluorescence when they are …
Pfam: a comprehensive database of protein domain families based on seed alignments
ELL Sonnhammer, SR Eddy… - … : Structure, Function, and …, 1997 - Wiley Online Library
Databases of multiple sequence alignments are a valuable aid to protein sequence
classification and analysis. One of the main challenges when constructing such a database …
classification and analysis. One of the main challenges when constructing such a database …
The SLCO (former SLC21) superfamily of transporters
B Hagenbuch, B Stieger - Molecular aspects of medicine, 2013 - Elsevier
The members of the organic anion transporting polypeptide superfamily (OATPs) are
classified within the SLCO solute carrier family. All functionally well characterized members …
classified within the SLCO solute carrier family. All functionally well characterized members …
Organic anion transporting polypeptides of the OATP/SLC21 family: phylogenetic classification as OATP/SLCO superfamily, new nomenclature and molecular …
B Hagenbuch, PJ Meier - Pflügers Archiv, 2004 - Springer
The organic anion transporting polypeptides (rodents: Oatps, human: OATPs) form a
superfamily of sodium-independent transport systems that mediate the transmembrane …
superfamily of sodium-independent transport systems that mediate the transmembrane …
Prostaglandin E2 synthesis and secretion: the role of PGE2 synthases
JY Park, MH Pillinger, SB Abramson - Clinical immunology, 2006 - Elsevier
Prostaglandin E2 (PGE2) is a principal mediator of inflammation in diseases such as
rheumatoid arthritis and osteoarthritis. Nonsteroidal anti-inflammatory medications (NSAIDs) …
rheumatoid arthritis and osteoarthritis. Nonsteroidal anti-inflammatory medications (NSAIDs) …
A membrane receptor for retinol binding protein mediates cellular uptake of vitamin A
R Kawaguchi, J Yu, J Honda, J Hu, J Whitelegge… - Science, 2007 - science.org
Vitamin A has diverse biological functions. It is transported in the blood as a complex with
retinol binding protein (RBP), but the molecular mechanism by which vitamin A is absorbed …
retinol binding protein (RBP), but the molecular mechanism by which vitamin A is absorbed …
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug–drug interactions
M Karlgren, A Vildhede, U Norinder… - Journal of medicinal …, 2012 - ACS Publications
The hepatic organic anion transporting polypeptides (OATPs) influence the
pharmacokinetics of several drug classes and are involved in many clinical drug–drug …
pharmacokinetics of several drug classes and are involved in many clinical drug–drug …
[HTML][HTML] The superfamily of organic anion transporting polypeptides
B Hagenbuch, PJ Meier - Biochimica et Biophysica Acta (BBA) …, 2003 - Elsevier
Organic anion transporting polypeptides (Oatps/OATPs) form a growing gene superfamily
and mediate transport of a wide spectrum of amphipathic organic solutes. Different …
and mediate transport of a wide spectrum of amphipathic organic solutes. Different …
Functional role of high-affinity anandamide transport, as revealed by selective inhibition
M Beltramo, N Stella, A Calignano, SY Lin… - Science, 1997 - science.org
Anandamide, an endogenous ligand for central cannabinoid receptors, is released from
neurons on depolarization and rapidly inactivated. Anandamide inactivation is not …
neurons on depolarization and rapidly inactivated. Anandamide inactivation is not …