Vaccines for visceral leishmaniasis: A review

K Jain, NK Jain - Journal of immunological methods, 2015 - Elsevier
Visceral leishmaniasis, which is also known as Kala-Azar, is one of the most severely
neglected tropical diseases recognized by the World Health Organization (WHO). The threat …

Case study for a vaccine against leishmaniasis

J Alvar, SL Croft, P Kaye, A Khamesipour, S Sundar… - Vaccine, 2013 - Elsevier
Leishmaniasis in many ways offers a unique vaccine case study. Two reasons for this are
that leishmaniasis is a disease complex caused by several different species of parasite that …

Mechanisms of immune evasion in leishmaniasis

G Gupta, S Oghumu, AR Satoskar - Advances in applied microbiology, 2013 - Elsevier
Diseases caused by Leishmania present a worldwide problem, and current therapeutic
approaches are unable to achieve a sterile cure. Leishmania is able to persist in host cells …

Design of a multi-epitope subunit vaccine for immune-protection against Leishmania parasite

S Yadav, J Prakash, H Shukla, KC Das… - Pathogens and global …, 2020 - Taylor & Francis
Visceral Leishmaniasis (VL) is an insect-borne neglected disease caused by the protozoan
parasite Leishmania donovani. In the absence of a commercial vaccine against VL …

Immunoadjuvant chemotherapy of visceral leishmaniasis in hamsters using amphotericin B-encapsulated nanoemulsion template-based chitosan nanocapsules

S Asthana, AK Jaiswal, PK Gupta… - Antimicrobial agents …, 2013 - Am Soc Microbiol
The accessible treatment options for life-threatening neglected visceral leishmaniasis (VL)
disease have problems with efficacy, stability, adverse effects, and cost, making treatment a …

[HTML][HTML] An immunoinformatic approach driven by experimental proteomics: in silico design of a subunit candidate vaccine targeting secretory proteins of Leishmania …

MAA Khan, JQ Ami, K Faisal, R Chowdhury, P Ghosh… - Parasites & vectors, 2020 - Springer
Background Visceral leishmaniasis (VL) caused by dimorphic Leishmania species is a
parasitic disease with high socioeconomic burden in endemic areas worldwide. Sustaining …

[HTML][HTML] Visceral leishmaniasis: advancements in vaccine development via classical and molecular approaches

S Joshi, K Rawat, NK Yadav, V Kumar… - Frontiers in …, 2014 - frontiersin.org
Visceral leishmaniasis (VL) or kala-azar, a vector-borne protozoan disease, shows
endemicity in larger areas of the tropical, subtropical and the Mediterranean countries. WHO …

[HTML][HTML] Recent updates and perspectives on approaches for the development of vaccines against visceral leishmaniasis

MC Duarte, DP Lage, VT Martins… - Revista da Sociedade …, 2016 - SciELO Brasil
Visceral leishmaniasis (VL) is one of the most important tropical diseases worldwide.
Although chemotherapy has been widely used to treat this disease, problems related to the …

Hamster, a close model for visceral leishmaniasis: Opportunities and challenges

S Saini, AK Rai - Parasite Immunology, 2020 - Wiley Online Library
Aim Visceral leishmaniasis (VL) caused by parasites belonging to genus Leishmania (L.) is
classified as a category I disease by the TDR/WHO. The understanding of the pathogenesis …

A new model of progressive visceral leishmaniasis in hamsters by natural transmission via bites of vector sand flies

H Aslan, R Dey, C Meneses… - The Journal of …, 2013 - academic.oup.com
Background. Visceral leishmaniasis (VL) is transmitted by sand flies. Protection of needle-
challenged vaccinated mice was abrogated in vector-initiated cutaneous leishmaniasis …