Liquid biopsy: a step closer to transform diagnosis, prognosis and future of cancer treatments

SN Lone, S Nisar, T Masoodi, M Singh, A Rizwan… - Molecular cancer, 2022 - Springer
Over the past decade, invasive techniques for diagnosing and monitoring cancers are slowly
being replaced by non-invasive methods such as liquid biopsy. Liquid biopsies have …

Biology, vulnerabilities and clinical applications of circulating tumour cells

A Ring, BD Nguyen-Sträuli, A Wicki, N Aceto - Nature Reviews Cancer, 2023 - nature.com
In recent years, exceptional technological advances have enabled the identification and
interrogation of rare circulating tumour cells (CTCs) from blood samples of patients, leading …

Single test-based diagnosis of multiple cancer types using Exosome-SERS-AI for early stage cancers

H Shin, BH Choi, O Shim, J Kim, Y Park, SK Cho… - Nature …, 2023 - nature.com
Early cancer detection has significant clinical value, but there remains no single method that
can comprehensively identify multiple types of early-stage cancer. Here, we report the …

Circulating tumour cells for early detection of clinically relevant cancer

R Lawrence, M Watters, CR Davies, K Pantel… - Nature Reviews Clinical …, 2023 - nature.com
Given that cancer mortality is usually a result of late diagnosis, efforts in the field of early
detection are paramount to reducing cancer-related deaths and improving patient outcomes …

Liquid biopsy of cancer: a multimodal diagnostic tool in clinical oncology

R Palmirotta, D Lovero, P Cafforio… - … in medical oncology, 2018 - journals.sagepub.com
Over the last decades, the concept of precision medicine has dramatically renewed the field
of medical oncology; the introduction of patient-tailored therapies has significantly improved …

The potential of liquid biopsy in the management of cancer patients

A Markou, E Tzanikou, E Lianidou - Seminars in cancer biology, 2022 - Elsevier
Over the last decade, liquid biopsy has gained much attention as a powerful tool in
personalized medicine, since it enables monitoring cancer evolution and follow-up of cancer …

A conduit to metastasis: circulating tumor cell biology

DS Micalizzi, S Maheswaran… - Genes & …, 2017 - genesdev.cshlp.org
Advances in the enrichment and analysis of rare cells from the bloodstream have allowed for
detection and characterization of circulating tumor cells (CTCs) from patients with cancer …

Circulating tumor DNA as biomarkers for cancer detection

X Han, J Wang, Y Sun - Genomics, Proteomics and …, 2017 - academic.oup.com
Detection of circulating tumor DNAs (ctDNAs) in cancer patients is an important component
of cancer precision medicine ctDNAs. Compared to the traditional physical and biochemical …

Liquid biopsies

E Lianidou, K Pantel - Genes, Chromosomes and Cancer, 2019 - Wiley Online Library
Liquid biopsy is based on minimally invasive blood tests and has a high potential to
significantly change the therapeutic strategy in cancer patients, providing an extremely …

[HTML][HTML] Prognostic significance of PD-L1 expression on circulating tumor cells in patients with head and neck squamous cell carcinoma

A Strati, G Koutsodontis, G Papaxoinis, I Angelidis… - Annals of …, 2017 - Elsevier
Background Successful application of programmed death 1 (PD1) checkpoint inhibitors in
the clinic may ultimately benefit from appropriate patient selection based upon predictive …