DNA methylation and cardiovascular disease in humans: a systematic review and database of known CpG methylation sites
M Krolevets, V Cate, JH Prochaska, A Schulz… - Clinical …, 2023 - Springer
Background Cardiovascular disease (CVD) is the leading cause of death worldwide and
considered one of the most environmentally driven diseases. The role of DNA methylation in …
considered one of the most environmentally driven diseases. The role of DNA methylation in …
On the use of blood samples for measuring DNA methylation in ecological epigenetic studies
A Husby - Integrative and Comparative Biology, 2020 - academic.oup.com
There is increasing interest in understanding the potential for epigenetic factors to contribute
to phenotypic diversity in evolutionary biology. One well studied epigenetic mechanism is …
to phenotypic diversity in evolutionary biology. One well studied epigenetic mechanism is …
Comparative analysis of genome-scale, base-resolution DNA methylation profiles across 580 animal species
J Klughammer, D Romanovskaia, A Nemc… - Nature …, 2023 - nature.com
Methylation of cytosines is a prototypic epigenetic modification of the DNA. It has been
implicated in various regulatory mechanisms across the animal kingdom and particularly in …
implicated in various regulatory mechanisms across the animal kingdom and particularly in …
Genome-wide identification of DNA methylation QTLs in whole blood highlights pathways for cardiovascular disease
Identifying methylation quantitative trait loci (meQTLs) and integrating them with disease-
associated variants from genome-wide association studies (GWAS) may illuminate …
associated variants from genome-wide association studies (GWAS) may illuminate …
Stress induced aging in mouse eye
Aging, a universal process that affects all cells in an organism, is a major risk factor for a
group of neuropathies called glaucoma, where elevated intraocular pressure is one of the …
group of neuropathies called glaucoma, where elevated intraocular pressure is one of the …
[HTML][HTML] Paternal preconception phthalate exposure alters sperm methylome and embryonic programming
Preconception environmental conditions have been demonstrated to shape sperm
epigenetics and subsequently offspring health and development. Our previous findings in …
epigenetics and subsequently offspring health and development. Our previous findings in …
Childhood trauma, the stress response and metabolic syndrome: a focus on DNA methylation
Childhood trauma (CT) is well established as a potent risk factor for the development of
mental disorders. However, the potential of adverse early experiences to exert chronic and …
mental disorders. However, the potential of adverse early experiences to exert chronic and …
Understanding the interplay between health disparities and epigenomics
Social epigenomics has emerged as an integrative field of research focused on identification
of socio-environmental factors, their influence on human biology through epigenomic …
of socio-environmental factors, their influence on human biology through epigenomic …
[HTML][HTML] Translational toxicoepigenetic meta-analyses identify homologous gene DNA methylation reprogramming following developmental phthalate and lead …
Although toxicology uses animal models to represent real-world human health scenarios, a
critical translational gap between laboratory-based studies and epidemiology remains. In …
critical translational gap between laboratory-based studies and epidemiology remains. In …
The relationship between the epigenetic aging biomarker “grimage” and lung function in both the airway and blood of people living with HIV: an observational cohort …
Background Age-related comorbidities such as chronic obstructive pulmonary disease
(COPD) are common in people living with human immunodeficiency virus (PLWH). We …
(COPD) are common in people living with human immunodeficiency virus (PLWH). We …