Significance of neutrophil to lymphocyte ratio (NLR) and platelet lymphocyte ratio (PLR) in diabetic foot ulcer and potential new therapeutic targets

D Serban, N Papanas, AM Dascalu… - … Journal of Lower …, 2024 - journals.sagepub.com
Diabetic foot ulcer (DFU) is a well-known complication of diabetes and a significant burden
on the national health systems. The neutrophil/lymphocyte ratio (NLR) and …

The role of neutrophils in diabetic ulcers and targeting therapeutic strategies

XX Ma, QK Liu, L Kuai, X Ma, Y Luo, Y Luo… - International …, 2023 - Elsevier
Diabetic ulcers (DUs) are a common complication of diabetes with high morbidity, poor
prognosis, and a high socio-economic burden. The main pathological manifestations of DUs …

Impact of red cell distribution width and red cell distribution width/albumin ratio on all-cause mortality in patients with type 2 diabetes and foot ulcers: a retrospective …

J Hong, X Hu, W Liu, X Qian, F Jiang, Z Xu… - Cardiovascular …, 2022 - Springer
Background Red blood cell distribution width (RDW) has emerged as a prognostic factor for
mortality in various diseases. Up to now, few studies have focused on the prognostic value …

Relationship between systemic immune inflammation index and amputation in patients with diabetic foot ulcer

MS Aydın, MA Eren, N Uyar, N Kankılıç… - Journal of Orthopaedic …, 2024 - Elsevier
Aim The systemic immune inflammation index (SII) is a cost-effective biomarker calculated
by lymphocyte, neutrophil and platelet counts and is currently being studied in various …

[HTML][HTML] IL-1B can serve as a healing process and is a critical regulator of diabetic foot ulcer

MS Gan, B Yang, DL Fang, BL Wu - Annals of Translational …, 2022 - ncbi.nlm.nih.gov
Background Diabetic foot ulcer (DFU) is the main cause of disability in diabetic patients.
However, the molecular changes underlying the occurrence and progression of DFU remain …

Effect of leukocyte-platelet fibrin-rich wound reconstruction followed by full-thickness skin grafting in the treatment of diabetic foot Wagner grade 4 ulcer gangrene (toe …

Y Wang, Y Wang, X Wang, Y Zhao, S Ruan, H Cao - Platelets, 2023 - Taylor & Francis
This study investigated the effect of L-PRF on promoting full-thickness skin grafting for the
treatment of diabetic foot ulcer wounds and attempted to characterize the mechanism. In a …

Analysis of NLR in Type 2 Diabetes Mellitus with and without Diabetic Foot Ulcer

R Ulandari, LB Kurniawan… - Indonesian …, 2023 -  …
Patients with type 2 diabetes mellitus (T2DM) have increased followed by complications
including diabetic foot ulcer. Systemic inflammatory conditions in T2DM with diabetic foot …

Association Between red Cell Distribution Width/Albumin Ratio and Diabetic Lower Extremity Ulcers (DLEU) among US Outpatients in the NHANES: A Retrospective …

D Huang, K Wang, T Deng, T Yang… - … International Journal of …, 2024 - journals.sagepub.com
Objective Diabetic foot ulcers are common chronic complications of diabetes mellitus that
can lead to amputation and death in severe cases. There is limited research on the …

Basic haematological tests as inflammatory performance markers of patients treated either by conservative surgery or minor amputation for infected diabetic foot ulcers

K Yammine, G Abou Orm, J Mouawad… - Wound Repair and …, 2023 - Wiley Online Library
Basic inflammatory markers have been extensively studied to differentiate between non‐
infected and infected diabetic foot ulcers (DFUs). Very rarely, basic haematological tests …

Blood cell count biomarkers, risk, and outcomes of ischemia-related lower limb amputations: A systematic review

P Dettori, AA Mangoni, A Zinellu… - … Journal of Lower …, 2022 - journals.sagepub.com
Lower limb amputations due to ischemia represent an important health care and social
issue. However, there are currently no specific biomarkers able to predict the risk of …