A critical analysis of research methods and experimental models to study pulpitis

R Richert, M Ducret, B Alliot‐Licht… - International …, 2022 - Wiley Online Library
Pulpitis is the inflammatory response of the dental pulp to a tooth insult, whether it is
microbial, chemical, or physical in origin. It is traditionally referred to as reversible or …

A guide to open science practices for animal research

K Diederich, K Schmitt, P Schwedhelm, B Bert… - PLoS …, 2022 - journals.plos.org
Translational biomedical research relies on animal experiments and provides the underlying
proof of practice for clinical trials, which places an increased duty of care on translational …

Biocompatibility analysis in subcutaneous tissue and physico-chemical analysis of pre-mixed calcium silicate–based sealers

ACP Janini, LE Pelepenko, JM Boldieri… - Clinical oral …, 2023 - Springer
Objectives To evaluate the biocompatibility, physical and chemical properties of three pre-
mixed calcium silicate–based sealers and an epoxy resin–based material were assessed …

Nano eggshell‐based slurry as a direct pulp‐capping material: In vitro characterization and histopathological assessment in an experimental animal model

S Nabil Sulyiman, AA El‐Rashidy… - International …, 2023 - Wiley Online Library
Aim Pulp vitality is essential for tooth integrity. Following pulp exposure, choosing a suitable
pulp‐capping material is crucial to maintain pulp vitality. However, the reparative dentine …

Biocompatibility and bioactive potential of an experimental tricalcium silicate‐based cement in comparison with Bio‐C repair and MTA Repair HP materials

MB Queiroz, RNH Inada, JLA Jampani… - International …, 2023 - Wiley Online Library
Aim To evaluate the tissue reaction of a tricalcium silicate‐based repair material associated
with 30% calcium tungstate (TCS+ CaWO4) in comparison to Bio‐C Repair (Bio‐C; Angelus) …

Inflammatory profile of apical periodontitis exacerbated by cigarette smoke inhalation: Histological and immunohistochemical analysis in rats

AMV Vasques, ACR da Silva… - International …, 2023 - Wiley Online Library
Aim The aim of this study was to evaluate the effects of cigarette smoke inhalation (CSI) on
inflammation, pro‐inflammatory mediators and haematological parameters in rats with …

Curcumin reduces inflammation in rat apical periodontitis

MP Justo, CBM Cardoso… - International …, 2022 - Wiley Online Library
Aim The aim of the study was to evaluate the effect of systemic curcumin administration on
the severity of apical periodontitis (AP). Methodology Forty male Wistar rats weighing 250 …

Does MTA provide a more favourable histological response than other materials in the repair of furcal perforations? A systematic review

LS Pinheiro, PMP Kopper, RM Quintana… - International …, 2021 - Wiley Online Library
Background There is no consensus on which furcal perforation repair material induces a
more favourable histological response. This systematic review of laboratory studies provides …

Cell proliferation, viability, differentiation, and apoptosis of iron oxide labeled stem cells transfected with lipofectamine assessed by MRI

R Jalli, D Mehrabani, S Zare… - Journal of Clinical …, 2023 - mdpi.com
To assess in vitro and in vivo tracking of iron oxide labeled stem cells transfected by
lipofectamine using magnetic resonance imaging (MRI), rat dental pulp stem cells (DPSCs) …

Gut microbiota may mediate the impact of chronic apical periodontitis on atherosclerosis in apolipoprotein E‐deficient mice

G Gan, R Zhang, B Lu, Y Luo, S Chen… - International …, 2023 - Wiley Online Library
Aim There are growing evidences linking chronic apical periodontitis (CAP) to
atherosclerosis. Gut microbiota is found to be involved in the development of …