The responses of patients to tumor therapies vary due to tumor heterogeneity. Tumor
stratification has been attracting increasing attention for accurately distinguishing between …

T cells are an essential part of the immune system with crucial roles in adaptive response
and the maintenance of tissue homeostasis. Depending on their microenvironment, T cells …

For fluorogenic probes, Förster resonance energy transfer (FRET) is one of the most widely
used mechanisms to realize the detection of biochemical activities. Dark quenchers relax …

Urinary monitoring of diseases has gained considerable attention due to its simple and non-
invasive sampling. However, urinalysis remains limited by the dearth of reliable urinary …

Despite numerous advances in the use of DNA as building blocks to assemble complex
structures, the dearth of strategies that allow for protease-controlled in situ DNA assembly in …

Resistance to immune checkpoint inhibitors (ICIs) is a major issue of the current era in
cancer immunotherapy. Immune evasion is a multi-factorial event, which occurs generally at …

Simultaneous detection of different biomarkers related to the spatiotemporally dynamic
immune events is of particular importance for the accurate evaluation of antitumor immune …

The last two decades have witnessed a major revolution in the field of tumor immunology
including clinical progress using various immunotherapy strategies. These advances have …

The forward design of biosensors that implement Boolean logic to improve detection
precision primarily relies on programming genetic components to control transcriptional …

Significant progress has been made in tumor immunotherapy that uses the human immune
response to kill and remove tumor cells. However, overreactive immune response could …