The human cathelicidin hCAP18/LL-37 has become a paradigm for the pleiotropic roles of
peptides in host defence. It has a remarkably wide functional repertoire that includes direct …

Life-threatening infectious diseases are on their way to cause a worldwide crisis, as treating
them effectively is becoming increasingly difficult due to the emergence of antibiotic resistant …

Motivation Bacterial resistance to antibiotics is a growing concern. Antimicrobial peptides
(AMPs), natural components of innate immunity, are popular targets for developing new …

The increased resistance of bacteria against conventional pharmaceutical solutions, the
antibiotics, has raised serious health concerns. This has stimulated interest in the …

As a key component of the innate immunity system, human cathelicidin LL-37 plays an
essential role in protecting humans against infectious diseases. To elucidate the structural …

Antimicrobial peptides (AMPs) are the natural antibiotics recognized for their broad-
spectrum resistance to bacteria, fungi, viruses and parasites, and influencing the host …

An important class of cytolytic antimicrobial peptides (AMPs) assumes an amphipathic, α-
helical conformation that permits efficient interaction with biological membranes. Host …

Antimicrobial peptides (AMPs) are molecules from innate immunity with high potential as
novel anti-infective agents. Most of them inactivate bacteria through pore formation or …

As the best substitute for antibiotics, antimicrobial peptides (AMPs) have important research
significance. Due to the high cost and difficulty of experimental methods for identifying …

Injectable hydrogels exhibiting self-healing ability are promising carriers for controlled and
sustained delivery in a minimally-invasive format for biomedical applications. We designed a …