Ceftolozane/tazobactam plus tobramycin against free-floating and biofilm bacteria of hypermutable Pseudomonas aeruginosa epidemic strains: Resistance …

AA Agyeman, C López-Causapé, KE Rogers… - International Journal of …, 2023 - Elsevier
Objective Acute exacerbations of biofilm-associated Pseudomonas aeruginosa infections in
cystic fibrosis (CF) have limited treatment options. Ceftolozane/tazobactam (alone and with a …

Clinical recommendations for the inpatient management of lower respiratory tract infections in children and adolescents with severe neurological impairment in …

MD Mauritz, U von Both, C Dohna-Schwake… - European Journal of …, 2024 - Springer
Children and adolescents with severe neurological impairment (SNI) require specialized
care due to their complex medical needs. In particular, these patients are often affected by …

Ceftazidime/Tobramycin Co-Loaded Chitosan-Coated Zein Nanoparticles against Antibiotic-Resistant and Biofilm-Producing Pseudomonas aeruginosa and …

LAA Campos, AFS Neto, AML Scavuzzi, ACDS Lopes… - Pharmaceuticals, 2024 - mdpi.com
This study aimed to co-encapsulate ceftazidime and tobramycin in zein nanoparticles coated
with chitosan and to characterize and evaluate the antibacterial and antibiofilm activity …

[HTML][HTML] Synergistic effects of inhaled aztreonam plus tobramycin on hypermutable cystic fibrosis Pseudomonas aeruginosa isolates in a dynamic biofilm model …

SKJ Breen, M Harper, C López-Causapé… - International journal of …, 2024 - Elsevier
Abstract Objective Hypermutable Pseudomonas aeruginosa strains are highly prevalent in
chronic lung infections of patients with cystic fibrosis (CF). Acute exacerbations of these …

Understanding the suitability of established antibiotics for oral inhalation from a pharmacokinetic perspective: an integrated model-based investigation based on …

A Himstedt, C Braun, SG Wicha… - Journal of Antimicrobial …, 2022 - academic.oup.com
Background Treating pulmonary infections by administering drugs via oral inhalation
represents an attractive alternative to usual routes of administration. However, the local …

Biofilm Producing Pseudomonas Aeruginosa in Patients with Lower Respiratory Tract Infections

S Rehman, S Najeeb, N Babar, S Zaman… - Pakistan Journal of …, 2022 - pjmhsonline.com
Abstract Background and Aim: Pseudomonas aeruginosa is a vital pathogen causing major
life-threatening infections among respiratory disease patients that leads to higher morbidity …