Gold complexes in anticancer therapy: From new design principles to particle‐based delivery systems
G Moreno‐Alcántar, P Picchetti… - Angewandte Chemie …, 2023 - Wiley Online Library
The discovery of the medicinal properties of gold complexes has fuelled the design and
synthesis of new anticancer metallodrugs, which have received special attention due to their …
synthesis of new anticancer metallodrugs, which have received special attention due to their …
Discovery of metal-based complexes as promising antimicrobial agents
J Liang, D Sun, Y Yang, M Li, H Li, L Chen - European Journal of Medicinal …, 2021 - Elsevier
The antimicrobial resistance (AMR) is an intractable problem for the world. Metal ions are
essential for the cell process and biological function in microorganisms. Many metal-based …
essential for the cell process and biological function in microorganisms. Many metal-based …
Simultaneous Activation of Immunogenic Cell Death and cGAS-STING Pathway by Liver-and Mitochondria-Targeted Gold (I) Complexes for Chemoimmunotherapy of …
F Li, Z Wen, C Wu, Z Yang, Z Wang… - Journal of Medicinal …, 2024 - ACS Publications
Induction of immunogenic cell death (ICD) and activation of the cyclic GMP-AMP synthase
stimulator of interferon gene (cGAS-STING) pathway are two potent anticancer …
stimulator of interferon gene (cGAS-STING) pathway are two potent anticancer …
Biotin-Targeted Au (I) radiosensitizer for cancer synergistic therapy by intervening with redox homeostasis and inducing ferroptosis
Z Yang, S Huang, Y Liu, X Chang, Y Liang… - Journal of Medicinal …, 2022 - ACS Publications
The search for highly selective sensitizers with a novel mechanism for tumor targeting
therapy is of considerable interest. In this work, we have developed a series of new biotin …
therapy is of considerable interest. In this work, we have developed a series of new biotin …
PEPPSI type Pd (II) NHC complexes bearing chloro-/fluorobenzyl group: Synthesis, characterization, crystal structures, α-glycosidase and acetylcholinesterase …
This work reported the synthesis of a new PEPPSI (Pyridine Enhanced Precatalyst
Preparation, Stabilization and Initiation) type Pd (II) N-heterocyclic carbene (NHC) …
Preparation, Stabilization and Initiation) type Pd (II) N-heterocyclic carbene (NHC) …
Synthesis, characterization and bioactivities of dative donor ligand N-heterocyclic carbene (NHC) precursors and their Ag (I) NHC coordination compounds
This study contains the synthesis of N-phthalimidomethyl-substituted NHC precursors and
their Ag (I) NHC coordination compounds. The NHC precursors were synthesized from the 1 …
their Ag (I) NHC coordination compounds. The NHC precursors were synthesized from the 1 …
Gold (III) derivatives in colon cancer treatment
A Gurba, P Taciak, M Sacharczuk… - International Journal of …, 2022 - mdpi.com
Cancer is one of the leading causes of morbidity and mortality worldwide. Colorectal cancer
(CRC) is the third most frequently diagnosed cancer in men and the second in women …
(CRC) is the third most frequently diagnosed cancer in men and the second in women …
A focus on the biological targets for coinage metal-NHCs as potential anticancer complexes
Metal complexes of N-heterocyclic carbene (NHC) ligands are the object of increasing
attention for therapeutic purposes. Among the different metal centres, interest on Au-based …
attention for therapeutic purposes. Among the different metal centres, interest on Au-based …
Novel Au carbene complexes as promising multi-target agents in breast cancer treatment
J Ceramella, A Mariconda, M Sirignano, D Iacopetta… - Pharmaceuticals, 2022 - mdpi.com
Over the past decade, metal complexes based on N-heterocyclic carbenes (NHCs) have
attracted great attention due to their wide and exciting applications in material sciences and …
attracted great attention due to their wide and exciting applications in material sciences and …
gold (I) bis (1, 2, 3-triazol-5-ylidene) complexes as promising selective anticancer compounds
JF Schlagintweit, CHG Jakob, NL Wilke… - Journal of Medicinal …, 2021 - ACS Publications
The synthesis and antiproliferative activity of Mes-and iPr-substituted gold (I) bis (1, 2, 3-
triazol-5-ylidene) complexes in various cancer cell lines are reported, showing nanomolar …
triazol-5-ylidene) complexes in various cancer cell lines are reported, showing nanomolar …