New finds in the palaeoanthropological and genomic records have changed our view of the
origins of modern human ancestry. Here we review our current understanding of how the …

The first decade of ancient genomics has revolutionized the study of human prehistory and
evolution. We review new insights based on prehistoric modern human genomes, including …

The human Y chromosome has been notoriously difficult to sequence and assemble
because of its complex repeat structure that includes long palindromes, tandem repeats and …

Modern humans appeared in Europe by at least 45,000 years ago 1, 2, 3, 4, 5, but the extent
of their interactions with Neanderthals, who disappeared by about 40,000 years ago 6, and …

The prevalence of highly repetitive sequences within the human Y chromosome has
prevented its complete assembly to date and led to its systematic omission from genomic …

INTRODUCTION Large-scale human genome-sequencing studies to date have been limited
to large, metropolitan populations or to small numbers of genomes from each group. Much …

RATIONALE To elucidate the extent to which the major cultural transformations of farming,
pastoralism, and shifts in the distribution of languages in Eurasia were accompanied by …

The vast majority of genome-wide association studies (GWASs) are performed in
Europeans, and their transferability to other populations is dependent on many factors (eg …

Northeastern Siberia has been inhabited by humans for more than 40,000 years but its deep
population history remains poorly understood. Here we investigate the late Pleistocene …

INTRODUCTION Genetic studies of the Pleistocene peopling of the Americas have focused
on the timing and number of migrations from Siberia into North America. They show that …