Functional imaging of the lungs with gas agents

SJ Kruger, SK Nagle, MJ Couch, Y Ohno… - Journal of Magnetic …, 2016 - Wiley Online Library
This review focuses on the state‐of‐the‐art of the three major classes of gas contrast agents
used in magnetic resonance imaging (MRI)—hyperpolarized (HP) gas, molecular oxygen …

Magnetic resonance imaging with hyperpolarized agents: methods and applications

EB Adamson, KD Ludwig, DG Mummy… - Physics in Medicine & …, 2017 - iopscience.iop.org
In the past decade, hyperpolarized (HP) contrast agents have been under active
development for MRI applications to address the twin challenges of functional and …

Protocols for multi‐site trials using hyperpolarized 129Xe MRI for imaging of ventilation, alveolar‐airspace size, and gas exchange: A position paper from the 129Xe …

PJ Niedbalski, CS Hall, M Castro… - Magnetic resonance …, 2021 - Wiley Online Library
Hyperpolarized (HP) 129Xe MRI uniquely images pulmonary ventilation, gas exchange, and
terminal airway morphology rapidly and safely, providing novel information not possible …

Registration-based assessment of regional lung function via volumetric CT images of normal subjects vs. severe asthmatics

S Choi, EA Hoffman, SE Wenzel… - Journal of applied …, 2013 - journals.physiology.org
The purpose of this work was to explore the use of image registration-derived variables
associated with computed tomographic (CT) imaging of the lung acquired at multiple …

Assessment of Regional Lung Function with Multivolume 1H MR Imaging in Health and Obstructive Lung Disease: Comparison with 3He MR Imaging

F Pennati, JD Quirk, DA Yablonskiy, M Castro, A Aliverti… - Radiology, 2014 - pubs.rsna.org
Purpose To introduce a method based on multivolume proton (hydrogen [1H]) magnetic
resonance (MR) imaging for the regional assessment of lung ventilatory function …

Lung magnetic resonance imaging: technical advancements and clinical applications

Y Ohno, Y Ozawa, H Nagata, T Ueda… - Investigative …, 2024 - journals.lww.com
Since lung magnetic resonance imaging (MRI) became clinically available, limited clinical
utility has been suggested for applying MRI to lung diseases. Moreover, clinical applications …

[HTML][HTML] Airspace Dimension Assessment (AiDA) by inhaled nanoparticles: benchmarking with hyperpolarised 129Xe diffusion-weighted lung MRI

M Petersson-Sjögren, HF Chan, GJ Collier… - Scientific Reports, 2021 - nature.com
Enlargements of distal airspaces can indicate pathological changes in the lung, but
accessible and precise techniques able to measure these regions are lacking. Airspace …

Pulmonary ventilation and micro‐structural findings in congenital diaphragmatic hernia

M Spoel, H Marshall, H IJsselstijn… - Pediatric …, 2016 - Wiley Online Library
Background With increasing survival of patients with more severe forms of congenital
diaphragmatic hernia (CDH) and risk of long‐term respiratory morbidity, studies on lung …

[HTML][HTML] Preclinical MRI Using Hyperpolarized 129Xe

S Kadlecek, Y Friedlander, RS Virgincar - Molecules, 2022 - mdpi.com
Although critical for development of novel therapies, understanding altered lung function in
disease models is challenging because the transport and diffusion of gases over short …

MR properties of 19FC3F8 gas in the lungs of healthy volunteers: and apparent diffusion coefficient at 1.5T and at 3T

A Maunder, HF Chan, PJC Hughes… - Magnetic …, 2021 - Wiley Online Library
Purpose To measure the transverse relaxation time () and apparent diffusion coefficient
(ADC) of 19F‐C3F8 gas in vivo in human lungs at 1.5 T and 3T, and to determine the …