Molecular and technical aspects on the interaction of serum albumin with multifunctional food preservatives

H Mohammadzadeh-Aghdash, N Akbari, K Esazadeh… - Food Chemistry, 2019 - Elsevier
Synthetic food preservatives like sodium acetate (SA), sodium benzoate (SB), potassium
sorbate (PS) and Butyl paraben (BP) have been widely used in food and pharmacy …

A comprehensive investigation of interactions between antipsychotic drug quetiapine and human serum albumin using multi-spectroscopic, biochemical, and …

S Zargar, TA Wani, NA Alsaif, AIA Khayyat - Molecules, 2022 - mdpi.com
Quetiapine (QTP) is a short-acting atypical antipsychotic drug that treats schizophrenia or
manic episodes of bipolar disorder. Human serum albumin (HSA) is an essential transport …

Probing the interaction between isoflucypram fungicides and human serum albumin: multiple spectroscopic and molecular modeling investigations

X Li, X Yan, D Yang, S Chen, H Yuan - International Journal of Molecular …, 2023 - mdpi.com
To better understand the potential toxicity risks of isoflucypram in humans, The interaction
between isoflucypram and HSA (human serum albumin) was studied through molecular …

Interaction of an abiraterone with calf thymus DNA: Investigation with spectroscopic technique and modelling studies

TA Wani, N Alsaif, AH Bakheit, S Zargar… - Bioorganic …, 2020 - Elsevier
Binding of toxic ligands to DNA could result in undesirable biological processes, such as
carcinogenesis or mutagenesis. Binding mode of Abiraterone (ABR), a steroid drug and calf …

Influence of antioxidant flavonoids quercetin and rutin on the in-vitro binding of neratinib to human serum albumin

TA Wani, AH Bakheit, S Zargar, ZS Alanazi… - … Acta Part A: Molecular …, 2021 - Elsevier
This study was designed to examine the interaction of neratinib (NRB) with human serum
albumin (HSA) in presence of flavonoids quercetin and rutin. Both quercetin and rutin can …

Profiling the interaction between human serum albumin and clinically relevant HIV reverse transcriptase inhibitors

A Costa-Tuna, OA Chaves, ZL Almeida, RS Cunha… - Viruses, 2024 - mdpi.com
Tenofovir (TFV) is the active form of the prodrugs tenofovir disoproxil fumarate (TDF) and
tenofovir alafenamide (TAF), both clinically prescribed as HIV reverse transcriptase …

Elucidation of molecular interactions of aspartic acid with aqueous potassium sorbate and sodium benzoate: Volumetric, viscometric and FTIR spectroscopic …

K Dhal, S Singh, M Talukdar - Journal of Molecular Liquids, 2022 - Elsevier
Aspartic acid (Asp), a nonessential amino acid has been taken for the present study.
Solutions of different concentrations of aspartic acid were prepared by dissolving it in water …

Interactions of cinnamaldehyde and its metabolite cinnamic acid with human serum albumin and interference of other food additives

Q Sun, H Yang, P Tang, J Liu, W Wang, H Li - Food chemistry, 2018 - Elsevier
Considering the adverse effect of food additives on humans, thorough research of their
physiological effects at the molecular level is important. The interactions of cinnamaldehyde …

A comprehensive biophysical and theoretical study on the binding of dexlansoprazole with human serum albumin

ATS Bodapati, RS Reddy, K Lavanya, SR Madku… - Journal of Molecular …, 2023 - Elsevier
Pharmacokinetics, pharmacodynamics, and therapeutic activity of drugs are defined by the
affinities between the drug and biological macromolecules through molecular recognition …

A spectroscopic, thermodynamic and molecular docking study of the binding mechanism of dapoxetine with calf thymus DNA

NA Alsaif, AA Al-Mehiziaa, AH Bakheit, S Zargar… - South African Journal of …, 2020 - ajol.info
Dapoxetine is a selective serotonin reuptake inhibitor, used to treat premature ejaculation in
men. Dapoxetine may interact with theDNAand hence this study investigated dapoxetine …