Air pollution is an issue of increasing interest due to its globally relevant impacts on
morbidity and mortality. Controlled human exposure (CHE) studies are often employed to …

In the past 2 years, there continue to be advances in our understanding of the genetic and
epigenetic underpinnings of atopy pertaining to disease risk and disease severity. The joint …

Human health and well-being are intricately linked to environmental quality. Environmental
exposures can have lifelong consequences. In particular, exposures during the vulnerable …

Epigenetic alterations, such as changes in DNA methylation, histones/chromatin structure,
nucleosome positioning, and expression of non-coding RNAs, are recognized among key …

Exposure to particulate matter (PM) from ambient air pollution is a well-known risk factor for
many lung diseases, but the mechanism (s) for this is not completely understood. Bronchial …

Diesel exhaust (DE) is a major component of air pollution in urban centers. Controlled
human exposure (CHE) experiments are commonly used to investigate the acute effects of …

Hypertension, a multifaceted cardiovascular disorder influenced by genetic, epigenetic, and
environmental factors, poses a significant risk for the development of coronary artery …

Air pollution is a significant environmental risk to health, leading to many diseases. People
with chronic respiratory diseases and children are especially vulnerable to detrimental …

This is an exciting time to be conducting asthma research. The recent development of
targeted asthma biologics has validated the power of basic research to discover new …

Background Exposure to traffic-related air pollution is associated with increased morbidity
and mortality. Negative health impact of diesel exhaust (DE) exposure may in part be …