Background Meta-analyses and single-site studies have established that children are less
infectious than adults within a household when positive for ancestral SARS-CoV-2. In …

Studies during the COVID-19 pandemic showed that children had heightened nasal innate
immune responses compared with adults. To evaluate the role of nasal viruses and bacteria …

Simple Summary Respiratory viral infections are among the most common diseases that
affect children. Respiratory syncytial virus (RSV) is the most common pathogen causing …

SARS-CoV-2 is the causative agent of the COVID-19 pandemic. Vaccination, supported by
social and public health measures, has proven efficacious for reducing disease severity and …

The severe acute respiratory syndrome coronavirus 2 pandemic is characterized by the
emergence of novel variants of concern (VOCs) that replace ancestral strains. Here, we …

Evolved SARS-CoV-2 variants of concern (VOCs) spread through human populations in
succession. Major virus variations are in the entry-facilitating viral spike (S) proteins; …

Abstract Background Knowledge of SARS-CoV-2 household transmission dynamics guides
infection control and vaccination measures. This household cohort study prospectively …

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is adapting to continuous
presence in humans. Transitions to endemic infection patterns are associated with changes …

Reverse zoonotic respiratory diseases threaten great apes across Sub-Saharan Africa.
Studies of wild chimpanzees have identified the causative agents of most respiratory …

Continuous assessment of the impact of SARS-CoV-2 on the host at the cell-type level is
crucial for understanding key mechanisms involved in host defense responses to viral …