The Tax1 oncoprotein encoded by Human T-lymphotropic virus type I is a major determinant
of viral persistence and pathogenesis. Tax1 affects a wide variety of cellular signalling …

▪ Abstract Many viruses utilize the cellular transcription apparatus to express their genomes,
and they encode transcriptional regulatory proteins that modulate the process. Here we …

Human T-cell lymphotropic virus type 1 (HTLV-1) has been identified as the causative agent
of adult T-cell leukemia (ATL) and HTLV-1-associated myelopathy/tropical spastic …

The human T-cell leukemia virus type 1 (HTLV-1) transcriptional trans-activator Tax has
been demonstrated to have transforming activity in multiple cell culture and transgenic …

Infection by HTLV-1 has been correlated with the appearance of various proliferative or
degenerative diseases. Some of these disorders have been observed in transgenic mice …

Abstract HTLV-1 and HTLV-2 are highly related complex retroviruses that have been studied
intensely for nearly three decades because of their association with neoplasia …

Human T lymphotropic viruses (HTLVs) are complex deltaretroviruses that do not contain a
proto-oncogene in their genome, yet are capable of transforming primary T lymphocytes …

Human T-cell lymphotropic virus type 1 (HTLV-1) transcriptional activation is mediated by
the viral transactivator, Tax, and three 21-bp repeats (Tax response element [TxRE]) located …

The human T-cell lymphotropic virus, type (HTLV)-1 trans-activator, Tax, coordinates with
cAMP-responsive element-binding protein (CREB) and the transcriptional co-activators …

The human T-cell leukemia virus type I or HTLV-I is the causative agent of adult T-cell
leukemia. A protein encoded by HTLV-I, Tax, activates viral gene expression and is …