The E. coli MinCDE system in the regulation of protein patterns and gradients
B Ramm, T Heermann, P Schwille - Cellular and Molecular Life Sciences, 2019 - Springer
Molecular self-organziation, also regarded as pattern formation, is crucial for the correct
distribution of cellular content. The processes leading to spatiotemporal patterns often …
distribution of cellular content. The processes leading to spatiotemporal patterns often …
Mechanochemical feedback loop drives persistent motion of liposomes
M Fu, T Burkart, I Maryshev, HG Franquelim… - Nature Physics, 2023 - nature.com
Achieving autonomous motion is a central objective in designing artificial cells that mimic
biological cells in form and function. Cellular motion often involves complex multiprotein …
biological cells in form and function. Cellular motion often involves complex multiprotein …
Self-organized protein patterns: The MinCDE and ParABS systems
Self-organized protein patterns are of tremendous importance for biological decision-making
processes. Protein patterns have been shown to identify the site of future cell division …
processes. Protein patterns have been shown to identify the site of future cell division …
Mass-sensitive particle tracking to elucidate the membrane-associated MinDE reaction cycle
T Heermann, F Steiert, B Ramm, N Hundt, P Schwille - Nature methods, 2021 - nature.com
In spite of their great importance in biology, methods providing access to spontaneous
molecular interactions with and on biological membranes have been sparse. The recent …
molecular interactions with and on biological membranes have been sparse. The recent …
MinE conformational switching confers robustness on self-organized Min protein patterns
J Denk, S Kretschmer, J Halatek… - Proceedings of the …, 2018 - National Acad Sciences
Protein patterning is vital for many fundamental cellular processes. This raises two intriguing
questions: Can such intrinsically complex processes be reduced to certain core principles …
questions: Can such intrinsically complex processes be reduced to certain core principles …
Stationary patterns in a two-protein reaction-diffusion system
P Glock, B Ramm, T Heermann, S Kretschmer… - ACS synthetic …, 2018 - ACS Publications
Patterns formed by reaction-diffusion mechanisms are crucial for the development or
sustenance of most organisms in nature. Patterns include dynamic waves, but are more …
sustenance of most organisms in nature. Patterns include dynamic waves, but are more …
Min oscillations in bacteria as real-time reporter of environmental challenges at the single-cell level
Min oscillations are a fascinating mechanism used by Escherichia coli to find their middle.
Beyond their biological role, they provide a convenient and relatively unexplored method to …
Beyond their biological role, they provide a convenient and relatively unexplored method to …
Forceful patterning: theoretical principles of mechanochemical pattern formation
Biological pattern formation is essential for generating and maintaining spatial structures
from the scale of a single cell to tissues and even collections of organisms. Besides …
from the scale of a single cell to tissues and even collections of organisms. Besides …
Non‐Equilibrium Large‐Scale Membrane Transformations Driven by MinDE Biochemical Reaction Cycles
The MinDE proteins from E. coli have received great attention as a paradigmatic biological
pattern‐forming system. Recently, it has surfaced that these proteins do not only generate …
pattern‐forming system. Recently, it has surfaced that these proteins do not only generate …
Mechanistic insights of the Min oscillator via cell-free reconstitution and imaging
K Mizuuchi, AG Vecchiarelli - Physical biology, 2018 - iopscience.iop.org
Abstract The MinD and MinE proteins of Escherichia coli self-organize into a standing-wave
oscillator on the membrane to help align division at mid-cell. When unleashed from cellular …
oscillator on the membrane to help align division at mid-cell. When unleashed from cellular …