Detection of progressive glaucomatous optic nerve damage on fundus photographs with deep learning

FA Medeiros, AA Jammal, EB Mariottoni - Ophthalmology, 2021 - Elsevier
Purpose To investigate whether predictions of retinal nerve fiber layer (RNFL) thickness
obtained from a deep learning model applied to fundus photographs can detect progressive …

Blood pressure and glaucomatous progression in a large clinical population

AA Jammal, SI Berchuck, EB Mariottoni, AP Tanna… - Ophthalmology, 2022 - Elsevier
Purpose To investigate the effect of systemic arterial blood pressure (BP) on rates of
progressive structural damage over time in glaucoma. Design Retrospective cohort study …

[HTML][HTML] Five-year visual field outcomes of the HORIZON trial

G Montesano, G Ometto, IIK Ahmed, PY Ramulu… - American journal of …, 2023 - Elsevier
PURPOSE To compare visual field (VF) progression between glaucoma patients receiving
cataract surgery alone (CS) or with a Hydrus microstent (CS-HMS). DESIGN Post hoc …

The effect of age on increasing susceptibility to retinal nerve fiber layer loss in glaucoma

AA Jammal, SI Berchuck, AC Thompson… - … & visual science, 2020 - iovs.arvojournals.org
Purpose: To determine whether aging modifies the effect of intraocular pressure (IOP) on
progressive glaucomatous retinal nerve fiber layer (RNFL) thinning over time. Methods: This …

Nanoparticles for the treatment of glaucoma-associated neuroinflammation

L Lambuk, NAA Suhaimi, MZ Sadikan, AJA Jafri… - Eye and Vision, 2022 - Springer
Recently, a considerable amount of literature has emerged around the theme of
neuroinflammation linked to neurodegeneration. Glaucoma is a neurodegenerative disease …

Rapid initial OCT RNFL thinning is predictive of faster visual field loss during extended follow-up in glaucoma

SS Swaminathan, AA Jammal, SI Berchuck… - American journal of …, 2021 - Elsevier
Purpose To investigate the relationship between the rate of retinal nerve fiber layer (RNFL)
loss during initial follow-up and the magnitude of associated visual field loss during an …

Validation of rates of mean deviation change as clinically relevant end points for glaucoma progression

FA Medeiros, AA Jammal - Ophthalmology, 2023 - Elsevier
Purpose To investigate whether rates of standard automated perimetry (SAP) mean
deviation (MD) over an initial 2-year follow-up period were predictive of events of visual field …

Deep learning–assisted detection of glaucoma progression in spectral-domain OCT

EB Mariottoni, S Datta, LS Shigueoka… - Ophthalmology …, 2023 - Elsevier
Purpose To develop and validate a deep learning (DL) model for detection of glaucoma
progression using spectral-domain (SD)-OCT measurements of retinal nerve fiber layer …

Predicting glaucoma development with longitudinal deep learning predictions from fundus photographs

T Lee, AA Jammal, EB Mariottoni… - American journal of …, 2021 - Elsevier
Purpose To assess whether longitudinal changes in a deep learning algorithm's predictions
of retinal nerve fiber layer (RNFL) thickness based on fundus photographs can predict future …

Fast progressors in glaucoma: prevalence based on global and central visual field loss

AB Jackson, KR Martin, MA Coote, FA Medeiros… - Ophthalmology, 2023 - Elsevier
Purpose To determine the prevalence of fast global and central visual field (VF) progression
in individuals with glaucoma under routine care. Design Observational study. Participants …