As management of respiratory distress syndrome (RDS) advances, clinicians must
continually revise their current practice. We report the fourth update of “European Guidelines …

The incidence of retinopathy of prematurity (ROP) is showing an increasing trend in the
United States. This may be because of increasing survival rates among extremely preterm …

Aim Neonates frequently require supplementary oxygen but may develop complications if
the oxygen saturation is outside the target range. This review aimed to determine whether …

Background Automated oxygen control systems are finding their way into contemporary
ventilators for preterm infants, each with its own algorithm, strategy and effect. Objective To …

Oxygen is the most common drug used in the neonatal intensive care. It has a narrow
therapeutic range in preterm infants. Too high (hyperoxemia) or low oxygen (hypoxemia) is …

Several studies demonstrated an increase in time spent within target range when automated
oxygen control (AOC) is used. However the effect on clinical outcome remains unclear. We …

For the preterm infant with respiratory insufficiency requiring supplemental oxygen, tight
control of oxygen saturation (SpO 2) is advocated, but difficult to achieve in practice …

Objective To evaluate the performance of a rapidly responsive adaptive algorithm (VDL1. 1)
for automated oxygen control in preterm infants with respiratory insufficiency. Design …

Objective To compare the effect of two different automated oxygen control devices on target
range (TR) time and occurrence of hypoxaemic and hyperoxaemic episodes. Design …

Aim To determine whether closed loop automated oxygen control resulted in a reduction in
the duration and severity of desaturation episodes and the number of blood gases and chest …