Multienzyme‐like nanozymes: regulation, rational design, and application

J Sheng, Y Wu, H Ding, K Feng, Y Shen… - Advanced …, 2024 - Wiley Online Library
Nanomaterials with more than one enzyme‐like activity are termed multienzymic
nanozymes, and they have received increasing attention in recent years and hold huge …

Catalase‐like nanozymes: Classification, catalytic mechanisms, and their applications

D Xu, L Wu, H Yao, L Zhao - Small, 2022 - Wiley Online Library
The field of nanozymes has developed rapidly over the past decade. Among various
oxidoreductases mimics, catalase (CAT)‐like nanozyme, acting as an essential part of the …

Depletable peroxidase-like activity of Fe3O4 nanozymes accompanied with separate migration of electrons and iron ions

H Dong, W Du, J Dong, R Che, F Kong… - Nature …, 2022 - nature.com
As pioneering Fe3O4 nanozymes, their explicit peroxidase (POD)-like catalytic mechanism
remains elusive. Although many studies have proposed surface Fe2+-induced Fenton-like …

Tumor‐microenvironment‐responsive cascade reactions by a cobalt‐single‐atom nanozyme for synergistic nanocatalytic chemotherapy

S Cai, J Liu, J Ding, Z Fu, H Li, Y Xiong… - Angewandte …, 2022 - Wiley Online Library
Nanocatalytic therapy, involving the nanozyme‐triggered production of reactive oxygen
species (ROS) in the tumor microenvironment (TME), has demonstrated potential in tumor …

Nanozymes-recent development and biomedical applications

X Ren, D Chen, Y Wang, H Li, Y Zhang, H Chen… - Journal of …, 2022 - Springer
Nanozyme is a series of nanomaterials with enzyme-mimetic activities that can proceed with
the catalytic reactions of natural enzymes. In the field of biomedicine, nanozymes are …

Nanozymes: A clear definition with fuzzy edges

H Wei, L Gao, K Fan, J Liu, J He, X Qu, S Dong… - Nano Today, 2021 - Elsevier
Recently, an editorial in ACS Catalysis entitled 'nano-apples and orange-zymes' questioned
whether or not the term “nanozyme” was appropriate [1]. When a new term in science is …

Nanozymes inspired by natural enzymes

R Zhang, X Yan, K Fan - Accounts of Materials Research, 2021 - ACS Publications
Conspectus Nanozymes, nanomaterials with enzyme-like activities with high structural
stability, adjustable catalytic activity, functional diversity, recyclability, and feasibility in large …

Nanozyme for tumor therapy: Surface modification matters

G Tang, J He, J Liu, X Yan, K Fan - Exploration, 2021 - Wiley Online Library
As the next generation of artificial enzymes, nanozymes have shown unique properties
compared to its natural counterparts, such as stability in harsh environment, low cost, and …

Ceria‐based therapeutic antioxidants for biomedical applications

YG Kim, Y Lee, N Lee, M Soh, D Kim… - Advanced …, 2024 - Wiley Online Library
The growing interest in nanomedicine over the last 20 years has carved out a research field
called “nanocatalytic therapy,” where catalytic reactions mediated by nanomaterials are …

Structure and activity of nanozymes: Inspirations for de novo design of nanozymes

Z Wang, R Zhang, X Yan, K Fan - Materials Today, 2020 - Elsevier
Nanozymes, nanomaterials with enzyme-like activities, are becoming powerful competitors
and potential substitutes for natural enzymes because of their excellent performance …