The in vitro panel of technologies to address biomolecular interactions are in play, however
microscale thermophoresis is continuously increasing in use to represent a key player in this …

Animal venoms comprise a complex mixture of components that affect several biological
systems. Based on the high selectivity for their molecular targets, these components are also …

Snakebite envenoming is the cause of an ongoing health crisis in several regions of the
world, particularly in tropical and neotropical countries. This scenario creates an urgent …

Varespladib (LY315920) is a potent inhibitor of human group IIA phospholipase A 2 (PLA 2)
originally developed to control inflammatory cascades of diseases associated with high or …

Viper venom phospholipase A2 enzymes (vvPLA2s) and phospholipase A2-like (PLA2-like)
proteins are two of the principal toxins in viper venom that are responsible for the severe …

Snakebite is a significant health concern in tropical and subtropical regions, particularly in
Africa, Asia, and Latin America, resulting in more than 2.7 million envenomations and an …

Background Specific compounds found in vegetal species have been demonstrated to be
efficient inhibitors of snake toxins, such as phospholipase A 2-like (PLA 2-like) proteins …

Snakebite envenomation has been categorized by World Health Organization as a category
A neglected tropical disease, since it causes chronic psychological disorders, physical …

Abstract Phospholipase A2 (PLA2) is one of the representative toxic components of snake
venom. PLA2s are categorized into several subgroups according to the amino acid at …

Snakebite envenomations result in acute and chronic physical and psychological health
effects on their victims, leading to a substantial socio-economic burden in tropical and …