Small-molecule probes from bench to bedside: advancing molecular analysis of drug–target interactions toward precision medicine

S Pan, A Ding, Y Li, Y Sun, Y Zhan, Z Ye… - Chemical Society …, 2023 - pubs.rsc.org
Over the past decade, remarkable advances have been witnessed in the development of
small-molecule probes. These molecular tools have been widely applied for interrogating …

Microfluidics on lensless, semiconductor optical image sensors: challenges and opportunities for democratization of biosensing at the micro-and nano-scale

X Hu, R Abbasi, S Wachsmann-Hogiu - Nanophotonics, 2023 - degruyter.com
Optical image sensors are 2D arrays of pixels that integrate semiconductor photodiodes and
field effect transistors for efficient photon conversion and processing of generated electrons …

Advances in exosome plasmonic sensing: Device integration strategies and AI-aided diagnosis

X Lin, J Zhu, J Shen, Y Zhang, J Zhu - Biosensors and Bioelectronics, 2024 - Elsevier
Exosomes, as next-generation biomarkers, has great potential in tracking cancer
progression. They face many detection limitations in cancer diagnosis. Plasmonic …

The role of nanodimensions in enhancing electrochemical sensing: A comprehensive review

M Jalali, SM Hosseini-Hosseinabad… - Chemical Engineering …, 2024 - Elsevier
Catalytic sensing of molecular biomarkers has become increasingly important in health
monitoring and point-of-care diagnostics due to their promising properties. To develop …

Bioelectric interface technologies in cells and organoids

Z Xue, J Zhao - Advanced Materials Interfaces, 2023 - Wiley Online Library
The past two decades have witnessed breakthroughs in cellular‐scale bioelectronics and
their widespread applications in life sciences, creating many powerful platforms for studying …

Identification of exosome protein panels as predictive biomarkers for non-small cell lung cancer

B Luo, Z Que, X Lu, D Qi, Z Qiao, Y Yang… - Biological Procedures …, 2023 - Springer
Background Non-small cell lung cancer (NSCLC) remains a leading cause of cancer-related
deaths worldwide, primarily due to its propensity for metastasis. Patients diagnosed with …

Size-exclusion chromatography-based extracellular vesicle size subtyping and multiplex membrane protein profiling for differentiating gastrointestinal cancer …

T Qin, P Li, J Li, Q Guo, Y Chen, YE Wang, L Tao… - Analyst, 2023 - pubs.rsc.org
Extracellular vesicles (EVs), as a type of subcellular structure, have been extensively
researched for their potential for developing advanced diagnostic technologies for various …

Compact highly sensitive photothermal RT-LAMP chip for simultaneous multidisease detection

W Guo, Y Tao, R Yang, K Mao, H Zhou, M Xu, T Sun… - Science …, 2024 - science.org
Developing instant detection systems with disease diagnostic capabilities holds immense
importance for remote or resource-limited areas. However, the task of creating these …

Pushing the Limits of Lateral Flow Immunoassay by Digital SERS for the Ultralow Detection of SARS‐CoV‐2 Virus

L González‐Cabaleiro, C Fernández‐Lodeiro… - Small …, 2024 - Wiley Online Library
Lateral flow immunoassays (LFIAs) are easy‐to‐use antigen tests that provide different
signal readouts, with colorimetric readouts being the most commonly used. However, these …

Magnetic augmentation through multi-gradient coupling enables direct and programmable profiling of circulating biomarkers

Y Chen, L Zhang, X Wu, X Sun, NR Sundah… - Nature …, 2024 - nature.com
Conventional magnetic biosensing technologies have reduced analytical capacity for
magnetic field dimensionality and require extensive sample processing. To address these …