Genomics and psychological resilience: a research agenda
Although exposure to adversity increases risk for poor mental health outcomes, many
people exposed to adversity do not develop such outcomes. Psychological resilience …
people exposed to adversity do not develop such outcomes. Psychological resilience …
Posttraumatic stress disorder and inflammation: untangling issues of bidirectionality
Posttraumatic stress disorder (PTSD) has increasingly been linked to heightened systemic
inflammation. It matters whether this association is causal (and either bidirectional or …
inflammation. It matters whether this association is causal (and either bidirectional or …
The genetics of the mood disorder spectrum: genome-wide association analyses of more than 185,000 cases and 439,000 controls
JRI Coleman, HA Gaspar, J Bryois, EM Byrne… - Biological …, 2020 - Elsevier
Background Mood disorders (including major depressive disorder and bipolar disorder)
affect 10% to 20% of the population. They range from brief, mild episodes to severe …
affect 10% to 20% of the population. They range from brief, mild episodes to severe …
Sex-stratified genome-wide association study of multisite chronic pain in UK Biobank
Chronic pain is highly prevalent worldwide and imparts a significant socioeconomic and
public health burden. Factors influencing susceptibility to, and mechanisms of, chronic pain …
public health burden. Factors influencing susceptibility to, and mechanisms of, chronic pain …
C‐reactive protein: Marker of risk for post‐traumatic stress disorder and its potential for a mechanistic role in trauma response and recovery
SF Friend, R Nachnani, SB Powell… - European Journal of …, 2022 - Wiley Online Library
Increasing evidence indicates that inflammation plays a role in PTSD and stress disorder
pathophysiology. PTSD is consistently associated with higher circulating inflammatory …
pathophysiology. PTSD is consistently associated with higher circulating inflammatory …
Genomic influences on self-reported childhood maltreatment
Childhood maltreatment is highly prevalent and serves as a risk factor for mental and
physical disorders. Self-reported childhood maltreatment appears heritable, but the specific …
physical disorders. Self-reported childhood maltreatment appears heritable, but the specific …
[HTML][HTML] Sex-stratified gene-by-environment genome-wide interaction study of trauma, posttraumatic-stress, and suicidality
Epidemiologic studies recognize that trauma and posttraumatic stress are associated with
heightened suicidal behavior severity, yet examination of these associations from a genetic …
heightened suicidal behavior severity, yet examination of these associations from a genetic …
Association of economic status and educational attainment with posttraumatic stress disorder: a Mendelian randomization study
Importance There is a well-established negative association of educational attainment (EA)
and other traits related to cognitive ability with posttraumatic stress disorder (PTSD), but the …
and other traits related to cognitive ability with posttraumatic stress disorder (PTSD), but the …
Association of polygenic risk scores and hair cortisol with mental health trajectories during COVID lockdown
KF Ahrens, RJ Neumann, NM von Werthern… - Translational …, 2022 - nature.com
The COVID-19 pandemic is a global stressor with inter-individually differing influences on
mental health trajectories. Polygenic Risk Scores (PRSs) for psychiatric phenotypes are …
mental health trajectories. Polygenic Risk Scores (PRSs) for psychiatric phenotypes are …
Shared genetic etiology underlying late‐onset Alzheimer's disease and posttraumatic stress syndrome
Abstract Introduction Late‐onset Alzheimer's disease (LOAD) manifests comorbid
neuropsychiatric symptoms and posttraumatic stress disorder (PTSD) is associated with an …
neuropsychiatric symptoms and posttraumatic stress disorder (PTSD) is associated with an …