[HTML][HTML] Enhanced hepatic glycogen synthesis and suppressed adenosine deaminase activity by lithium attenuates hepatic triglyceride accumulation in nicotine …

EO Dangana, OS Michael, TE Omolekulo… - Biomedicine & …, 2019 - Elsevier
Reduced liver glycogen synthesis might signify increased glucose flux towards fat synthesis
and triggers hepatic triglyceride accumulation and dysmetabolism. Adenosine deaminase …

Ameliorative effect of nicotine exposure on insulin resistance is accompanied by decreased cardiac glycogen synthase kinase-3 and plasminogen activator inhibitor-1 …

OS Michael, LA Olatunji - Archives of physiology and biochemistry, 2018 - Taylor & Francis
Context: Cigarette smoking is considered to be a major risk factor for the development of
diabetes and cardiovascular disease. Oestrogen-progestin combined oral contraceptive …

Blockade of mineralocorticoid receptor ameliorates oral contraceptive-induced insulin resistance by suppressing elevated uric acid and glycogen synthase kinase-3 …

OA Adeyanju, OS Michael, AO Soladoye… - Archives of Physiology …, 2020 - Taylor & Francis
Context: Estrogen–progestin combined oral contraceptive (COC) has been connected to
mineralocorticoid receptor (MR) activation and adverse cardiometabolic events. We …

[HTML][HTML] Dipeptidyl peptidase-4 inhibition protects the liver of insulin-resistant female rats against triglyceride accumulation by suppressing uric acid

TE Omolekulo, OS Michael, LA Olatunji - Biomedicine & Pharmacotherapy, 2019 - Elsevier
Abstract Dipeptidyl peptidase-4 (DPP-4) inhibition has been shown to exert beneficial effects
against insulin resistance (IR) and type 2 diabetes. Combined oral contraceptive (COC) …

Oral hormonal therapy with ethinylestradiol–levonorgestrel improves insulin resistance, obesity, and glycogen synthase kinase-3 independent of circulating …

OA Adeyanju, OA Soetan, AO Soladoye… - Canadian Journal of …, 2018 - cdnsciencepub.com
Estrogen deficiency has been associated with increased incidence of cardiovascular
diseases, and recent clinical trials of standard formulations of hormonal therapies have not …

Allopurinol and valproic acid improve cardiac triglyceride and Na+-K+-ATPase activity independent of circulating aldosterone in female rats with glucose intolerance

TE Adegoke, IW Sabinari, TO Usman… - … of Physiology and …, 2022 - Taylor & Francis
Context: Studies have shown that cardiac triglyceride accumulation and impaired Na+-K+-
ATPase activity are linked to diabetes-related cardiovascular disease, particularly in women …

[HTML][HTML] Drospirenone-containing oral contraceptives do not affect glucose regulation and circulating corticosterone

OA Adeyanju, LA Olatunji - Journal of Basic and Clinical Physiology …, 2019 - degruyter.com
Background Combined oral contraceptive (COC) use has been associated with an
increased risk of insulin resistance (IR) and other adverse cardiovascular events, despite …

Low-dose spironolactone ameliorates insulin resistance and suppresses elevated plasminogen activator inhibitor-1 during gestational testosterone exposure

LA Olatunji, TO Usman, AI Akinade… - … of Physiology and …, 2017 - Taylor & Francis
Context: Elevated gestational circulating testosterone has been associated with pathological
pregnancies that increase the risk of development of cardiometabolic disorder in later life …

Nicotine exposure suppresses hyperinsulinemia and improves endothelial dysfunction mediators independent of corticosteroids in insulin-resistant oral contraceptive …

OS Michael, LA Olatunji - Drug and chemical toxicology, 2018 - Taylor & Francis
Estrogen-progestin oral contraceptives (COC) or tobacco smoking has been associated with
hypertension and endothelial dysfunction resulting in increased risk of cardiovascular …

Sodium acetate improves disrupted glucoregulation and hepatic triglyceride content in insulin-resistant female rats: involvement of adenosine deaminase and …

TE Omolekulo, OS Michael, LA Olatunji - … -Schmiedeberg's Archives of …, 2019 - Springer
Combined oral contraceptive (COC) treatment has been shown to be associated with
glucose deregulation and increased triglyceride levels, but the mechanisms are elusive …