An update on animal models of intervertebral disc degeneration and low back pain: exploring the potential of artificial intelligence to improve research analysis and …
Animal models have been invaluable in the identification of molecular events occurring in
and contributing to intervertebral disc (IVD) degeneration and important therapeutic targets …
and contributing to intervertebral disc (IVD) degeneration and important therapeutic targets …
[HTML][HTML] Total disc replacement devices: structure, material, fabrication, and properties
The intervertebral disc (IVD) is an important component of the human spine that maintains
physiological motion and distributes loads. Single-or multi-segment degeneration occurs …
physiological motion and distributes loads. Single-or multi-segment degeneration occurs …
Structural mechanisms in soft fibrous tissues: a review
M Sharabi - Frontiers in Materials, 2022 - frontiersin.org
Through years of evolution, biological soft fibrous tissues have developed remarkable
functional properties, unique hierarchical architectures, and-most notably, an unparalleled …
functional properties, unique hierarchical architectures, and-most notably, an unparalleled …
[HTML][HTML] Synchrotron tomography of intervertebral disc deformation quantified by digital volume correlation reveals microstructural influence on strain patterns
The intervertebral disc (IVD) has a complex and multiscale extracellular matrix structure
which provides unique mechanical properties to withstand physiological loading. Low back …
which provides unique mechanical properties to withstand physiological loading. Low back …
The ultrastructural organization of elastic fibers at the interface of the nucleus and annulus of the intervertebral disk
There has been no study to describe the ultrastructural organization of elastic fibers at the
interface of the nucleus pulposus and annulus fibrosus of the intervertebral disk (IVD), a …
interface of the nucleus pulposus and annulus fibrosus of the intervertebral disk (IVD), a …
Quantifying deformations and strains in human intervertebral discs using Digital Volume Correlation combined with MRI (DVC-MRI)
Physical disruptions to intervertebral discs (IVDs) can cause mechanical changes that lead
to degeneration and to low back pain which affects 75% of us in our lifetimes. Quantifying …
to degeneration and to low back pain which affects 75% of us in our lifetimes. Quantifying …
Structure-function characterization of the transition zone in the intervertebral disc
M Mirzaeipoueinak, HS Mordechai, SS Bangar… - Acta Biomaterialia, 2023 - Elsevier
Understanding the structure-function relationship in the intervertebral disk (IVD) is crucial for
the development of novel tissue engineering strategies to regenerate IVD and the …
the development of novel tissue engineering strategies to regenerate IVD and the …
[HTML][HTML] The influence of geometry on intervertebral disc stiffness
Geometry plays an important role in intervertebral disc (IVD) mechanics. Previous
computational studies have found a link between IVD geometry and stiffness. However, few …
computational studies have found a link between IVD geometry and stiffness. However, few …
The mechanical role of the radial fiber network within the annulus fibrosus of the lumbar intervertebral disc: a finite elements study
M Sharabi, A Levi-Sasson… - Journal of …, 2019 - asmedigitalcollection.asme.org
The annulus fibrosus (AF) of the intervertebral disc (IVD) consists of a set of concentric
layers composed of a primary circumferential collagen fibers arranged in an alternating …
layers composed of a primary circumferential collagen fibers arranged in an alternating …
Towards intervertebral disc engineering: Bio-mimetics of form and function of the annulus fibrosus lamellae
M Sharabi, S Wertheimer, KR Wade… - Journal of the …, 2019 - Elsevier
The aging western society is heavily afflicted with intervertebral disc (IVD) degeneration.
Replacement or repair of the degenerated IVD with an artificial bio-mimetic construct is one …
Replacement or repair of the degenerated IVD with an artificial bio-mimetic construct is one …