[HTML][HTML] Sperm DNA fragmentation: a new guideline for clinicians

A Agarwal, A Majzoub, S Baskaran… - The world journal of …, 2020 - ncbi.nlm.nih.gov
Sperm DNA integrity is crucial for fertilization and development of healthy offspring. The
spermatozoon undergoes extensive molecular remodeling of its nucleus during later phases …

Sperm cryodamage in ruminants: understanding the molecular changes induced by the cryopreservation process to optimize sperm quality

P Peris-Frau, AJ Soler, M Iniesta-Cuerda… - International journal of …, 2020 - mdpi.com
Sperm cryopreservation represents a powerful tool for livestock breeding. Several efforts
have been made to improve the efficiency of sperm cryopreservation in different ruminant …

Diet and nutritional factors in male (in) fertility—underestimated factors

K Skoracka, P Eder, L Łykowska-Szuber… - Journal of clinical …, 2020 - mdpi.com
In up to 50% of cases, infertility issues stem solely from the male. According to some data,
the quality of human semen has deteriorated by 50%–60% over the last 40 years. A high-fat …

Oxidative stress and male fertility: role of antioxidants and inositols

MN De Luca, M Colone, R Gambioli, A Stringaro… - Antioxidants, 2021 - mdpi.com
Infertility is defined as a couple's inability to conceive after at least one year of regular
unprotected intercourse. This condition has become a global health problem affecting …

Oxidative stress in the pathophysiology of male infertility

C Ritchie, EY Ko - Andrologia, 2021 - Wiley Online Library
The effects of reactive oxygen species on male fertility are governed by the oxidative
paradox, defined by a delicate balance between oxidative stress and antioxidant capacity …

Oxidative stress and male infertility: the protective role of antioxidants

A Kaltsas - Medicina, 2023 - mdpi.com
Oxidative stress is a significant factor in male infertility, compromising sperm function and
overall reproductive health. As male infertility garners increasing attention, effective …

Role of antioxidants in cooled liquid storage of mammal spermatozoa

MA Silvestre, JL Yániz, FJ Peña, P Santolaria… - Antioxidants, 2021 - mdpi.com
Cooled preservation of semen is usually associated with artificial insemination and genetic
improvement programs in livestock species. Several studies have reported an increase in …

Melatonin alleviates heat stress-induced oxidative stress and apoptosis in human spermatozoa

F Zhao, S Whiting, S Lambourne, RJ Aitken… - Free Radical Biology and …, 2021 - Elsevier
Oxidative stress generates a large amount of reactive oxygen species (ROS) and affects
sperm quality via damaging sperm DNA and compromising the intracellular homeostasis in …

Hallmarks of testicular aging: the challenge of anti-inflammatory and antioxidant therapies using natural and/or pharmacological compounds to improve the …

ME Matzkin, RS Calandra, SP Rossi, A Bartke… - Cells, 2021 - mdpi.com
The evolutionary theory of aging supports a trade-off relationship between reproduction and
aging. Aging of the male reproductive system primarily affects the testes, leading to a …

[HTML][HTML] Utility of antioxidants in the treatment of male infertility: clinical guidelines based on a systematic review and analysis of evidence

A Agarwal, K Leisegang, A Majzoub… - The world journal of …, 2021 - ncbi.nlm.nih.gov
It is widely accepted that oxidative stress plays an important role in the pathophysiology of
male infertility and that antioxidants could have a significant role in the treatment of male …