The interplay between chromatin, transcription factors and genes generates complex
regulatory circuits that can be represented as gene regulatory networks (GRNs). The study …

Transcription factors (TFs) are key regulators of intrinsic cellular processes, such as
differentiation and development, and of the cellular response to external perturbation …

Background The binding of transcription factors (TF) to genomic targets is critical in the
regulation of gene expression. Short, double-stranded DNA sequence motifs are routinely …

Gene activation requires the cooperative activity of multiple transcription factors at cis-
regulatory elements (CREs). Yet, most transcription factors have short residence time …

Enhancers are genomic DNA elements controlling spatiotemporal gene expression. Their
flexible organization and functional redundancies make deciphering their sequence-function …

How transcription factors attain their target gene specificity and how this specificity may be
modulated, acquiring different regulatory functions through the development of plant tissues …

Transcription factors (TFs) play a critical role in determining cell fate decisions by integrating
developmental and environmental signals through binding to specific cis-regulatory …

Cooperative DNA-binding by transcription factor (TF) proteins is critical for eukaryotic gene
regulation. In the human genome, many regulatory regions contain TF-binding sites in close …

Forkhead box (FOX) proteins are an evolutionarily conserved family of transcription factors
that play numerous regulatory roles in eukaryotes during developmental and adult life …

Neuronal stimulation induced by the brain‐derived neurotrophic factor (BDNF) triggers gene
expression, which is crucial for neuronal survival, differentiation, synaptic plasticity, memory …