Three‐dimensional multicellular biomaterial platforms for biomedical application
J Hao, C Qin, C Wu - Interdisciplinary Materials, 2023 - Wiley Online Library
Abstract The three‐dimensional (3D) multicellular platforms prepared by cells or
biomaterials have been widely applied in biomedical fields for the regeneration of complex …
biomaterials have been widely applied in biomedical fields for the regeneration of complex …
In Situ Fabrication of Constraints for Multicellular Micro‐Spheroids Using Two‐Photon Lithography
M Taale, B Schamberger, F Taheri… - Advanced Functional …, 2024 - Wiley Online Library
photon polymerization is a promising technology for creating complex, microscale 3D
matrices for biomedical and also bioprinting applications. Cancer research provides …
matrices for biomedical and also bioprinting applications. Cancer research provides …
Dynamics of macrophage tumor infiltration
Long-term remission in cancer patients treated with ex vivo bona fide M1-induced
macrophages has been poor, and the reasons behind this are not understood. Injected M1 …
macrophages has been poor, and the reasons behind this are not understood. Injected M1 …
[HTML][HTML] Systemic Nos2 Depletion and Cox inhibition limits TNBC disease progression and alters lymphoid cell spatial orientation and density
Antitumor immune polarization is a key predictor of clinical outcomes to cancer therapy. An
emerging concept influencing clinical outcome involves the spatial location of CD8+ T cells …
emerging concept influencing clinical outcome involves the spatial location of CD8+ T cells …
Breast cancer immunity: it is TIME for the next chapter
DF Quail, M Park, AL Welm… - Cold Spring …, 2024 - perspectivesinmedicine.cshlp.org
Our ability to interrogate the tumor immune microenvironment (TIME) at an ever-increasing
granularity has uncovered critical determinants of disease progression. Not only do we now …
granularity has uncovered critical determinants of disease progression. Not only do we now …
Self‐Produced O2 CNs‐Based Nanocarriers of DNA Hydrophobization Strategy Triggers Photodynamic and Mitochondrial‐Derived Ferroptosis for Hepatocellular …
MX Liu, YC Liu, YT Cai, YY Gu, YQ Zhu… - Advanced …, 2024 - Wiley Online Library
Hypoxia can aggravate tumor occurrence, development, invasion, and metastasis, and
greatly inhibit the photodynamic therapy (PDT) effect. Herein, carbon nitride (CNs)‐based …
greatly inhibit the photodynamic therapy (PDT) effect. Herein, carbon nitride (CNs)‐based …
Biofabrication of Modular Spheroids as Tumor‐Scale Microenvironments for Drug Screening
To streamline the drug discovery pipeline, there is a pressing need for preclinical models
which replicate the complexity and scale of native tumors. While there have been …
which replicate the complexity and scale of native tumors. While there have been …
In vitro miniaturized tuberculosis spheroid model
Tuberculosis (TB) is a public health concern that impacts 10 million people around the
world. Current in vitro models are low throughput and/or lack caseation, which impairs drug …
world. Current in vitro models are low throughput and/or lack caseation, which impairs drug …
7-Amino-6H-anthra [9, 1-cd] Isothiazol-6-one-Casein Nanosystem for Live Cell Staining and Augmenting Therapeutic Effectiveness in Triple Negative Breast Cancer
Triple negative breast cancer (TNBC) causes a significant challenge in oncology due to its
aggressive nature and limited treatment options. This study introduces a promising strategy …
aggressive nature and limited treatment options. This study introduces a promising strategy …
Hypoxia, acidification and oxidative stress in cells cultured at large distances from an oxygen source
N D'Aiuto, J Hochmann, M Millán, A Di Paolo… - Scientific reports, 2022 - nature.com
Hypoxia is a condition frequently encountered by cells in tissues, whether as a normal
feature of their microenvironment or subsequent to deregulated growth. Hypoxia can lead to …
feature of their microenvironment or subsequent to deregulated growth. Hypoxia can lead to …