The use of biomarkers as early warning systems in the evaluation of disease risk has
increased markedly in the last decade. Biomarkers are indicators of typical biological …

Sports-related concussion (SRC) is defined as a mild traumatic brain injury (mTBI) leading to
complex impairment (s) in neurological function with many seemingly hidden or difficult to …

Background: Digital health technologies are attracting attention as novel tools for data
collection in clinical research. They present alternative methods compared to in-clinic data …

Digital health technologies (DHTs) enable us to measure human physiology and behavior
remotely, objectively and continuously. With the accelerated adoption of DHTs in clinical …

Artificial intelligence (AI) is transforming many domains, including finance, agriculture,
defense, and biomedicine. In this paper, we focus on the role of AI in clinical and …

Background: Digital measures offer an unparalleled opportunity to create a more holistic
picture of how people who are patients behave in their real-world environments, thereby …

Abstract The US Food and Drug Administration (FDA) has publicly recognized the
importance of improving drug development efficiency, deeming translational biomarkers a …

Abstract The EVIDENCE (EValuatIng connecteD sENsor teChnologiEs) checklist was
developed by a multidisciplinary group of content experts convened by the Digital Medicine …

Apps are becoming an increasingly important component of modern Public Health and
health care. However, successful implementation of apps does not come without challenges …

Depression is an invalidating disorder, marked by phenotypic heterogeneity. Clinical
assessments for treatment adjustments and data-collection for pharmacological research …