Synthetic and medicinal perspective of antileishmanial agents: an overview
S Pawar, MK Kumawat, M Kundu, K Kumar - Journal of Molecular Structure, 2023 - Elsevier
Leishmaniasis is one of the most common neglected tropical diseases (NTD), and is
originated in over 98 countries, affecting about 12 million people every year, which is …
originated in over 98 countries, affecting about 12 million people every year, which is …
[HTML][HTML] Antiparasitic effects of sulfated polysaccharides from marine hydrobionts
NN Besednova, TS Zaporozhets, BG Andryukov… - Marine Drugs, 2021 - mdpi.com
This review presents materials characterizing sulfated polysaccharides (SPS) of marine
hydrobionts (algae and invertebrates) as potential means for the prevention and treatment of …
hydrobionts (algae and invertebrates) as potential means for the prevention and treatment of …
[HTML][HTML] Modulation of Macrophage Redox and Apoptotic Processes to Leishmania infantum during Coinfection with the Tick-Borne Bacteria Borrelia burgdorferi
D Pessôa-Pereira, BM Scorza, KI Cyndari, EA Beasley… - Pathogens, 2023 - mdpi.com
Canine leishmaniosis (CanL) is a zoonotic disease caused by protozoan Leishmania
infantum. Dogs with CanL are often coinfected with tick-borne bacterial pathogens, including …
infantum. Dogs with CanL are often coinfected with tick-borne bacterial pathogens, including …
[HTML][HTML] Synthesis of 1,2,3-Triazole-Containing Methoxylated Cinnamides and Their Antileishmanial Activity against the Leishmania braziliensis Species
FS Santos, RP Freitas, CS Freitas, DVC Mendonça… - Pharmaceuticals, 2023 - mdpi.com
Leishmaniasis is a group of infectious diseases caused by protozoan parasites that belong
to the genus Leishmania. Currently, there is no human vaccine, and the available treatments …
to the genus Leishmania. Currently, there is no human vaccine, and the available treatments …
Global Remodeling of Host Proteome in Response to Leishmania Infection
E Reyaz, N Puri, A Selvapandiyan - ACS Infectious Diseases, 2023 - ACS Publications
The protozoan parasite Leishmania possesses an intrinsic ability to modulate a multitude of
pathways in the host, toward aiding its own proliferation. In response, the host reprograms its …
pathways in the host, toward aiding its own proliferation. In response, the host reprograms its …
[HTML][HTML] The role of apoptosis and oxidative stress in the pathophysiology of Acanthamoeba spp. infection in the kidneys of hosts with different immunological status
K Kot, P Kupnicka, M Tarnowski, P Tomasiak… - Parasites & …, 2023 - Springer
Background Acanthamoeba spp. are opportunistic pathogens that cause inflammation,
mostly in the brain, lungs and cornea. Recent reports indicate kidney dysfunction in hosts …
mostly in the brain, lungs and cornea. Recent reports indicate kidney dysfunction in hosts …
[HTML][HTML] Prosopis juliflora (Sw.) DC. induces apoptotic-like programmed cell death in Leishmania donovani via over production of oxidative stress, mitochondrial …
Background Leishmaniasis is endemic in more than 60 countries with a large number of
mortality cases. The current chemotherapy approaches employed for managing the …
mortality cases. The current chemotherapy approaches employed for managing the …
[HTML][HTML] Manipulation of Macrophages: Emerging Mechanisms of Leishmaniasis
D Nandan, HK Brar, N Reiner - Frontiers in Bioscience-Landmark, 2024 - imrpress.com
As professional phagocytes, macrophages represent the first line of defence against
invading microbial pathogens. Various cellular processes such as programmed cell death …
invading microbial pathogens. Various cellular processes such as programmed cell death …
A Novel Role of Secretory Cytosolic Tryparedoxin Peroxidase in Delaying Apoptosis of Leishmania-Infected Macrophages
S Das, T Saha, S Yadav, C Shaha - Molecular and Cellular …, 2022 - Am Soc Microbiol
The cytosolic tryparedoxin peroxidase (cTXNPx) of Leishmania donovani is a defensive
enzyme. Apart from the nonsecretory form, the cTXNPx is released in the spent media of …
enzyme. Apart from the nonsecretory form, the cTXNPx is released in the spent media of …
Assessing the effects of Leishmania (Leishmania) infantum and L.(L.) amazonensis infections in macrophages using a quantitative proteome approach
IHR Oliveira, F Kjeldsen, MN Melo-Braga… - Experimental …, 2022 - Elsevier
Leishmania (Leishmania) infantum is the causative agent of visceral leishmaniasis, while
L.(L.) amazonensis is associated with localized cutaneous and diffuse leishmaniasis, which …
L.(L.) amazonensis is associated with localized cutaneous and diffuse leishmaniasis, which …