The global incidence of Chronic Kidney Disease (CKD) is steadily escalating, with
discernible linkage to the intricate terrain of intestinal microecology. The intestinal microbiota …

Background Cardiovascular diseases persist as the primary cause of mortality in the global
population. Hypertension (HTN) is widely recognized as one of the most crucial risk factors …

Ethnopharmacological relevance Pulsatilla decoction has been extensively used to treat
ulcerative colitis (UC) in recent years. Pulsatilla chinensis saponin (PRS), the active …

Olfr78, which is a novel receptor for short‐chain fatty acid (SCFA) acetate and propionate,
plays essential roles in some cellular processes. The present study aimed to investigate the …

G-protein-coupled receptors (GPCRs) are critical regulators of cardiac physiology and a key
therapeutic target for the treatment of heart disease. Ectopic olfactory receptors (ORs) are …

Congenital heart disease (CHD) is a prevalent birth defect and a significant contributor to
childhood mortality. The major characteristics of CHD include cardiovascular malformations …

There is a “popular” belief that a fat-free diet is beneficial, supported by the scientific dogma
indicating that high levels of faty acids promote many pathological metabolic …

Resveratrol, acting as a prebiotic, and propionate, functioning as a postbiotic, hold promise
for preventing hypertension in chronic kidney disease (CKD). Previously, we employed …

Short-chain fatty acids (SCFAs) produced by the gut bacteria have been associated with
cardiovascular dysfunction in humans and rodents. However, studies exploring effects of …

Antrodia cinnamomea (AC), a medicinal mushroom, has multiple beneficial actions, such as
acting as a prebiotic. The incidence of chronic kidney disease (CKD) in children has steadily …