Despite improvements in awareness and treatment of type II diabetes mellitus (TIIDM), this
disease remains a major source of morbidity and mortality worldwide, and prevalence …

Free radicals, reactive oxygen/nitrogen species (ROS/RNS), hydrogen sulphide, and
hydrogen peroxide play an important role in both intracellular and intercellular signaling; …

Type 2 diabetes mellitus (DM) has reached pandemic proportions and effective prevention
strategies are wanted. Its onset is accompanied by cellular distress, the nuclear factor …

Diabetes mellitus occurrence has been associated to the modification of the physiological
levels of glucose and is often accompanied by several long-term complications, namely …

Magnesium (in its ionized and biologically active form, Mg 2+) is an essential trace element
that participates in numerous physiologic processes. Abnormal Mg 2+ homeostasis can lead …

Atherosclerosis is a chronic inflammatory disease of the vascular arterial walls. A number of
studies have revealed the biological and genetic bases of atherosclerosis, and over 100 …

The pathogenic processes involving in the development of diabetes range from autoimmune
destruction of pancreatic β-cells with consequent insulin deficiency to abnormalities that …

Diabetic nephropathy (DN) is the most serious chronic complications of diabetes; 20–40% of
diabetic patients develop into end stage renal disease (ESRD). However, exact …

Diabetic cardiomyopathy and nephropathy are two major causes of death of patients with
diabetes. Extra generation of reactive oxygen species (ROS), induced by hyperglycemia, is …

NAD (P) H: quinone oxidoreductase (NQO) is an antioxidant flavoprotein that catalyzes the
reduction of highly reactive quinone metabolites by employing NAD (P) H as an electron …