Cancer and inflammation interlink with many pathways. Millions of people died because of
these two disorders. Major pathways that cause both inflammation and cancer are STAT3 …

Febuxostat, initially developed as a xanthine oxidase inhibitor to address hyperuricemia in
gout patients, has evolved into a versatile therapeutic agent with multifaceted applications …

The prevalence of gout and the adverse effects of current synthetic anti-gout drugs call for
new natural and effective xanthine oxidase (XOD) inhibitors to target this disease. Based on …

Abstract Treatment of gout involves two basic approaches: reducing the serum uric acid
mainly by xanthine oxidase inhibitors (XOIs) and alleviating the intensity of the …

Objective: To evaluate the photoprotective, antioxidant, antiglycation, and antiacne activities
of crude extract (CESs) and triterpene saponin fraction (TSSs) of Sapindus saponaria …

Background The occurrence of gout is closely related to metabolism, but there is still a lack
of evidence on the causal role of metabolites in promoting or preventing gout. Methods We …

The superoxide radical ion is involved in numerous physiological processes, associated
with both health and pathology. Its participation in cancer onset and progression is well …

This research describes the synthesis by an environmentally-friendly method, microwave
irradiation, development and analysis of three novel and one previously identified Schiff …

Background This study aimed to explore the potential roles of Vδ2 T cells in the
pathogenesis of acute gouty arthritis. Methods Patients with gout (n= 86), rheumatoid …

Objective To determine the role of nerve injury-induced protein 1 (NINJ1) introduced plasma
membrane rupture (PMR) and damage-associated molecular patterns (DAMPs) release in …