Linking plant secondary metabolites and plant microbiomes: a review

Z Pang, J Chen, T Wang, C Gao, Z Li, L Guo… - Frontiers in plant …, 2021 - frontiersin.org
Plant secondary metabolites (PSMs) play many roles including defense against pathogens,
pests, and herbivores; response to environmental stresses, and mediating organismal …

Best practices for analysing microbiomes

R Knight, A Vrbanac, BC Taylor, A Aksenov… - Nature Reviews …, 2018 - nature.com
Complex microbial communities shape the dynamics of various environments, ranging from
the mammalian gastrointestinal tract to the soil. Advances in DNA sequencing technologies …

NetCoMi: network construction and comparison for microbiome data in R

S Peschel, CL Müller, E Von Mutius… - Briefings in …, 2021 - academic.oup.com
Motivation Estimating microbial association networks from high-throughput sequencing data
is a common exploratory data analysis approach aiming at understanding the complex …

Recovery of gut microbiota of healthy adults following antibiotic exposure

A Palleja, KH Mikkelsen, SK Forslund, A Kashani… - Nature …, 2018 - nature.com
To minimize the impact of antibiotics, gut microorganisms harbour and exchange antibiotics
resistance genes, collectively called their resistome. Using shotgun sequencing-based …

Microbiome datasets are compositional: and this is not optional

GB Gloor, JM Macklaim, V Pawlowsky-Glahn… - Frontiers in …, 2017 - frontiersin.org
Datasets collected by high-throughput sequencing (HTS) of 16S rRNA gene amplimers,
metagenomes or metatranscriptomes are commonplace and being used to study human …

[HTML][HTML] From diversity to complexity: Microbial networks in soils

K Guseva, S Darcy, E Simon, LV Alteio… - Soil Biology and …, 2022 - Elsevier
Network analysis has been used for many years in ecological research to analyze
organismal associations, for example in food webs, plant-plant or plant-animal interactions …

[HTML][HTML] Linear and nonlinear correlation estimators unveil undescribed taxa interactions in microbiome data

H Lin, M Eggesbø, SD Peddada - Nature communications, 2022 - nature.com
It is well-known that human gut microbiota form an ecosystem where microbes interact with
each other. Due to complex underlying interactions, some microbes may correlate …

[HTML][HTML] Network analysis methods for studying microbial communities: A mini review

MS Matchado, M Lauber, S Reitmeier… - Computational and …, 2021 - Elsevier
Microorganisms including bacteria, fungi, viruses, protists and archaea live as communities
in complex and contiguous environments. They engage in numerous inter-and intra …

Normalization and microbial differential abundance strategies depend upon data characteristics

S Weiss, ZZ Xu, S Peddada, A Amir, K Bittinger… - Microbiome, 2017 - Springer
Background Data from 16S ribosomal RNA (rRNA) amplicon sequencing present
challenges to ecological and statistical interpretation. In particular, library sizes often vary …

Microbiome-wide association studies link dynamic microbial consortia to disease

JA Gilbert, RA Quinn, J Debelius, ZZ Xu, J Morton… - Nature, 2016 - nature.com
Rapid advances in DNA sequencing, metabolomics, proteomics and computational tools are
dramatically increasing access to the microbiome and identification of its links with disease …