Systems pharmacology for investigation of the mechanisms of action of traditional Chinese medicine in drug discovery

W Zhang, Y Huai, Z Miao, A Qian… - Frontiers in pharmacology, 2019 - frontiersin.org
As a traditional medical intervention in Asia and a complementary and alternative medicine
in western countries, traditional Chinese medicine (TCM) has attracted global attention in …

[HTML][HTML] TCM Fingerprint database: a digital approach to scientifically reflect the internal quality of traditional Chinese medicine

Q Wang, N Wei, L Xu, H Hua, J Li, Y Jiang… - … Modern Chinese Medicine, 2023 - Elsevier
Abstract Background Traditional Chinese medicine (TCM) has been used to prevent, treat
and diagnose diseases for 5,000 years under the guidance of TCM theories. TCM …

Prediction of the mechanisms of action of Shenkang in chronic kidney disease: a network pharmacology study and experimental validation

T Qin, L Wu, Q Hua, Z Song, Y Pan, T Liu - Journal of ethnopharmacology, 2020 - Elsevier
Abstract Ethnopharmacological relevance Traditional Chinese medicine provides a unique
curative treatment of complex chronic diseases, including chronic kidney disease (CKD) …

Exploring active ingredients and function mechanisms of Ephedra-bitter almond for prevention and treatment of Corona virus disease 2019 (COVID-19) based on …

K Gao, YP Song, A Song - BioData mining, 2020 - Springer
Background COVID-19 has caused a global pandemic, and there is no wonder drug for
epidemic control at present. However, many clinical practices have shown that traditional …

Investigate the mechanisms of Chinese medicine Fuzhengkangai towards EGFR mutation-positive lung adenocarcinomas by network pharmacology

Z Bing, Z Cheng, D Shi, X Liu, J Tian, X Yao… - … and Alternative Medicine, 2018 - Springer
Background Chinese traditional herbal medicine Fuzhengkangai (FZKA) formulation
combination with gefitinib can overcome drug resistance and improve the prognosis of lung …

Evidence or delusion: a critique of contemporary rhino horn demand reduction strategies

HN Dang Vu, MR Nielsen - Human Dimensions of Wildlife, 2021 - Taylor & Francis
Considerable effort has been devoted to reducing rhinoceros (ie, rhino) horn demand by
changing consumer behavior. Implementing organizations often claim that their campaigns …

[HTML][HTML] Network pharmacology based research into the effect and mechanism of Xijiao Dihuang decoction against sepsis

J Lu, J Yan, J Yan, L Zhang, M Chen, Q Chen… - Biomedicine & …, 2020 - Elsevier
Sepsis is a critical illness that contributes a high mortality, while Xijiao Dihuang decoction
(XJDHT) has been used in treatment against sepsis for many years by clinical doctors …

A network pharmacology study on the molecular mechanisms of FDY003 for breast cancer treatment

HS Lee, IH Lee, K Kang, SI Park… - Evidence‐Based …, 2021 - Wiley Online Library
Herbal medicines have drawn considerable attention with regard to their potential
applications in breast cancer (BC) treatment, a frequently diagnosed malignant disease …

Niujiaodihuang detoxify decoction inhibits ferroptosis by enhancing glutathione synthesis in acute liver failure models

Y Ji, W Si, J Zeng, L Huang, Z Huang, L Zhao… - Journal of …, 2021 - Elsevier
Abstract Ethnopharmacological relevance Niujiaodihuang Detoxify Decoction (NDD) is an
integrated traditional Chinese medicine prescription that has been used as a therapeutic …

Systems pharmacology analysis of synergy of TCM: an example using saffron formula

J Liu, J Liu, F Shen, Z Qin, M Jiang, J Zhu, Z Wang… - Scientific Reports, 2018 - nature.com
Traditional Chinese medicine (TCM) follows the principle of formulae, in which the
pharmacological activity of a single herb can be enhanced or potentiated by addition of …