Class A PBPs: It is time to rethink traditional paradigms
D Straume, KW Piechowiak, M Kjos… - Molecular …, 2021 - Wiley Online Library
Until recently, class A penicillin‐binding proteins (aPBPs) were the only enzymes known to
catalyze glycan chain polymerization from lipid II in bacteria. Hence, the discovery of two …
catalyze glycan chain polymerization from lipid II in bacteria. Hence, the discovery of two …
Toward a mechanistic understanding of bacterial rod shape formation and regulation
EC Garner - Annual Review of Cell and Developmental Biology, 2021 - annualreviews.org
One of the most common bacterial shapes is a rod, yet we have a limited understanding of
how this simple shape is constructed. While only six proteins are required for rod shape, we …
how this simple shape is constructed. While only six proteins are required for rod shape, we …
FtsZ treadmilling is essential for Z-ring condensation and septal constriction initiation in Bacillus subtilis cell division
KD Whitley, C Jukes, N Tregidgo, E Karinou… - Nature …, 2021 - nature.com
Despite the central role of division in bacterial physiology, how division proteins work
together as a nanoscale machine to divide the cell remains poorly understood. Cell division …
together as a nanoscale machine to divide the cell remains poorly understood. Cell division …
Roles of RodZ and class A PBP1b in the assembly and regulation of the peripheral peptidoglycan elongasome in ovoid‐shaped cells of Streptococcus pneumoniae …
RodZ of rod‐shaped bacteria functions to link MreB filaments to the Rod peptidoglycan (PG)
synthase complex that moves circumferentially perpendicular to the long cell axis, creating …
synthase complex that moves circumferentially perpendicular to the long cell axis, creating …
MurA escape mutations uncouple peptidoglycan biosynthesis from PrkA signaling
S Wamp, P Rothe, D Stern, G Holland, J Döhling… - PLoS …, 2022 - journals.plos.org
Gram-positive bacteria are protected by a thick mesh of peptidoglycan (PG) completely
engulfing their cells. This PG network is the main component of the bacterial cell wall, it …
engulfing their cells. This PG network is the main component of the bacterial cell wall, it …
Metabolic Control of Cell Elongation and Cell Division in Bacillus subtilis
A Galinier, E Foulquier, F Pompeo - Frontiers in Microbiology, 2021 - frontiersin.org
To survive and adapt to changing nutritional conditions, bacteria must rapidly modulate cell
cycle processes, such as doubling time or cell size. Recent data have revealed that cellular …
cycle processes, such as doubling time or cell size. Recent data have revealed that cellular …
The role of cell-envelope synthesis for envelope growth and cytoplasmic density in Bacillus subtilis
All cells must increase their volumes in response to biomass growth to maintain intracellular
mass density within physiologically permissive bounds. Here, we investigate the regulation …
mass density within physiologically permissive bounds. Here, we investigate the regulation …
Cell-envelope synthesis is required for surface-to-mass coupling, which determines dry-mass density in Bacillus subtilis
Cells must increase their volumes in response to biomass growth to maintain intracellular
mass density, the ratio of dry mass to cell volume, within physiologically permissive bounds …
mass density, the ratio of dry mass to cell volume, within physiologically permissive bounds …