Calcitonin gene-related peptide (CGRP) is a neuropeptide with diverse physiological
functions. Its two isoforms (α and β) are widely expressed throughout the body in sensory …

The understanding of migraine pathophysiology is advancing rapidly. Improved
characterisation and diagnosis of its clinical features have led to the view of migraine as a …

Background Neuroinflammation has an important role in the pathophysiology of migraine,
which is a complex neuro-glio-vascular disorder. The main aim of this review is to highlight …

Background Migraine is a complex neurovascular disorder with a strong genetic component.
There are rare monogenic forms of migraine, as well as more common polygenic forms; …

Chronic migraine is a neurological disorder characterized by 15 or more headache days per
month of which at least 8 days show typical migraine features. The process that describes …

There is substantial evidence indicating a role for glutamate in migraine. Levels of glutamate
are higher in the brain and possibly also in the peripheral circulation in migraine patients …

Migraine is a leading cause of disability worldwide, but it is still underdiagnosed and
undertreated. Research on the pathophysiology of this neurological disease led to the …

Several non-mental diseases seem to be associated with an increased risk of ADHD and
ADHD seems to be associated with increased risk for non-mental diseases. The underlying …

Objective To identify natural subgroups of people with migraine based on profiles of
comorbidities and concomitant conditions, hereafter referred to as comorbidities …

ABSTRACT Introduction Calcitonin Gene-Related Peptide (CGRP) has gradually emerged
as a suitable therapeutic target to treat migraine. Considering the social and economic …