Affecting nearly 80 million individuals, glaucoma is the number one cause of irreversible
blindness in the world. This ocular disease describes a set of optic neuropathies of which …

Glaucoma, the world's leading cause of irreversible blindness, is a complex disease, with
differential presentation as well as ethnic and geographic disparities. The multifactorial …

Primary open-angle glaucoma (POAG), the leading cause of irreversible blindness
worldwide, disproportionately affects individuals of African ancestry. We conducted a …

Personalized medicine has been identified as a powerful tool for addressing the myriad of
health issues facing different health systems globally. Although recent studies have …

Over the last decade, genetic studies, including genome-wide association studies (GWAS),
have accelerated the discovery of genes and genomic regions contributing to primary open …

Normal-pressure glaucoma (NPG) is part of the spectrum of the open-angle glaucomas and
morphologically characterized, as any glaucoma, by a loss of neuroretinal rim parallel to an …

Genome-wide association studies (GWASs) of eye disorders have identified hundreds of
genetic variants associated with ocular disease. However, the vast majority of these variants …

Chronically elevated intraocular pressure (IOP) is the major risk factor of primary open-angle
glaucoma, a leading cause of blindness. Dysfunction of the trabecular meshwork (TM) …

Glaucoma is the leading cause of irreversible blindness worldwide. Primary open-angle
glaucoma (POAG), the most common glaucoma subtype, is more prevalent and severe in …

Glaucoma refers to a heterogenous group of disorders characterised by progressive loss of
retinal ganglion cells and associated visual field loss. Both early‐onset and adult‐onset …