Maternal immune activation by poly I: C as a preclinical model for neurodevelopmental disorders: a focus on autism and schizophrenia
Maternal immune activation (MIA) in response to a viral infection during early and mid-
gestation has been linked through various epidemiological studies to a higher risk for the …
gestation has been linked through various epidemiological studies to a higher risk for the …
[HTML][HTML] Maternal immune activation and the development of dopaminergic neurotransmission of the offspring: relevance for schizophrenia and other psychoses
A Aguilar-Valles, B Rodrigue… - Frontiers in Psychiatry, 2020 - frontiersin.org
Prenatal infections have been linked to the development of schizophrenia (SCZ) and other
neurodevelopmental disorders in the offspring, and work in animal models indicates that this …
neurodevelopmental disorders in the offspring, and work in animal models indicates that this …
Adolescence is a sensitive period for prefrontal microglia to act on cognitive development
SM Schalbetter, AS von Arx, N Cruz-Ochoa… - Science …, 2022 - science.org
The prefrontal cortex (PFC) is a cortical brain region that regulates various cognitive
functions. One distinctive feature of the PFC is its protracted adolescent maturation, which is …
functions. One distinctive feature of the PFC is its protracted adolescent maturation, which is …
[HTML][HTML] Sex-dependent behavioral deficits and neuropathology in a maternal immune activation model of autism
O Haida, T Al Sagheer, A Balbous… - Translational …, 2019 - nature.com
Infections during gestation and the consequent maternal immune activation (MIA) increase
the risk of developing neuropsychiatric disorders in infants and throughout life, including …
the risk of developing neuropsychiatric disorders in infants and throughout life, including …
Maternal infection and stress during pregnancy and depressive symptoms in adolescent offspring
SK Murphy, AM Fineberg, SD Maxwell, LB Alloy… - Psychiatry …, 2017 - Elsevier
Maternal infection during pregnancy has been linked to increased risk of offspring
depression. Additionally, maternal stress during pregnancy has been consistently linked …
depression. Additionally, maternal stress during pregnancy has been consistently linked …
Behavioral tasks evaluating schizophrenia-like symptoms in animal models: a recent update
MJ Ang, S Lee, JC Kim, SH Kim… - Current …, 2021 - ingentaconnect.com
Background: Schizophrenia is a serious mental illness that affects more than 21 million
people worldwide. Both genetics and the environment play a role in its etiology and …
people worldwide. Both genetics and the environment play a role in its etiology and …
[HTML][HTML] Maternal immune activation during pregnancy impacts on brain structure and function in the adult offspring
S Kreitz, A Zambon, M Ronovsky, L Budinsky… - Brain, Behavior, and …, 2020 - Elsevier
Gestational infection constitutes a risk factor for the occurrence of psychiatric disorders in the
offspring. Activation of the maternal immune system (MIA) with subsequent impact on the …
offspring. Activation of the maternal immune system (MIA) with subsequent impact on the …
Functional connectivity of the ventral tegmental area and avolition in subjects with schizophrenia: a resting state functional MRI study
Avolition, a deficit in goal-directed behavior, is a key aspect of negative symptoms. It is
highly prevalent in schizophrenia and is associated to poor functional outcome and to …
highly prevalent in schizophrenia and is associated to poor functional outcome and to …
[HTML][HTML] Interaction between maternal immune activation and peripubertal stress in rats: impact on cocaine addiction-like behaviour, morphofunctional brain …
Substance use disorders are more prevalent in schizophrenia, but the causal links between
both conditions remain unclear. Maternal immune activation (MIA) is associated with …
both conditions remain unclear. Maternal immune activation (MIA) is associated with …
[HTML][HTML] Prefrontal microglia deficiency during adolescence disrupts adult cognitive functions and synaptic structures: A follow-up study in female mice
AS von Arx, K Dawson, HY Lin, D Mattei… - Brain, Behavior, and …, 2023 - Elsevier
The prefrontal cortex (PFC) provides executive top-down control of a variety of cognitive
processes. A distinctive feature of the PFC is its protracted structural and functional …
processes. A distinctive feature of the PFC is its protracted structural and functional …