Medications to treat disease and extend life in our patients often amass in quantities,
resulting in what has been termed “polypharmacy.” This imprecise label usually describes …

Compared with younger people, elderly people show age‐related sleep changes, including
an advanced sleep phase and decreased slow‐wave sleep, which result in fragmented …

Importance Although concern exists regarding the rate of benzodiazepine use, especially
long-term use by older adults, little information is available concerning patterns of …

Objectives To investigate the relation between the risk of Alzheimer's disease and exposure
to benzodiazepines started at least five years before, considering both the dose-response …

PRESCRIPTION DRUGS ARE THE THIRD LEADING CAUSE OF DEATH AFTER HEART
DISEASE AND CANCER. In his latest ground-breaking book, Peter C Gotzsche exposes the …

A decade has passed since we published a comprehensive review in this journal
addressing the topic of promoting successful cognitive aging, making this a good time to …

Management of benzodiazepine misuse and dependence - PMC Back to Top Skip to main
content NIH NLM Logo Access keys NCBI Homepage MyNCBI Homepage Main Content Main …

Objective To determine whether higher cumulative use of benzodiazepines is associated
with a higher risk of dementia or more rapid cognitive decline. Design Prospective …

Background: Benzodiazepines are a widely used medication in developed countries,
particularly among elderly patients. However, benzodiazepines are known to affect memory …

Objective To test the hypothesis that people taking anxiolytic and hypnotic drugs are at
increased risk of premature mortality, using primary care prescription records and after …