Angiogenesis in non-small cell lung cancer: the prognostic impact of neoangiogenesis and the cytokines VEGF and bFGF in tumours and blood
BACKGROUND: Due to a dismal prognosis of advanced lung cancer, novel screening tools
and more effective treatments are clearly needed. Lately, an increasing number of tumour …
and more effective treatments are clearly needed. Lately, an increasing number of tumour …
[HTML][HTML] Multifunctional CD40L: pro-and anti-neoplastic activity
A Korniluk, H Kemona, V Dymicka-Piekarska - Tumor Biology, 2014 - Springer
The CD40 ligand is a type I transmembrane protein that belongs to a tumor necrosis factor
(TNF) superfamily. It is present not only on the surface of activated CD4+ T cells, B cells …
(TNF) superfamily. It is present not only on the surface of activated CD4+ T cells, B cells …
Circulating D‐dimer levels are better predictors of overall survival and disease progression than carcinoembryonic antigen levels in patients with metastatic colorectal …
K Blackwell, H Hurẃitz, G Liebérman… - … Journal of the …, 2004 - Wiley Online Library
BACKGROUND Fibrin formation is required for tumor angiogenesis, metastasis, and
invasion. D‐dimer, a fibrin degradation product, is produced when crosslinked fibrin is …
invasion. D‐dimer, a fibrin degradation product, is produced when crosslinked fibrin is …
Predictive value of D-dimer plasma levels in response and progressive disease in patients with lung cancer
D Antoniou, G Pavlakou, GP Stathopoulos, I Karydis… - Lung Cancer, 2006 - Elsevier
Patients with cancer may present with one or more circulatory markers of haemostatic
activation which may be associated with tumor growth and cancer cell dissemination. In our …
activation which may be associated with tumor growth and cancer cell dissemination. In our …
[HTML][HTML] Hyperfibrinogenemia is associated with lymphatic as well as hematogenous metastasis and worse clinical outcome in T2 gastric cancer
H Yamashita, J Kitayama, N Kanno, Y Yatomi… - BMC cancer, 2006 - Springer
Background Abnormal hemostasis in cancer patients has previously been described,
however the correlation between the plasma fibrinogen level and cancer metastasis and …
however the correlation between the plasma fibrinogen level and cancer metastasis and …
Platelet activation, coagulation and angiogenesis in breast and prostate carcinoma
GJ Caine, GYH Lip, PS Stonelake… - Thrombosis and …, 2004 - thieme-connect.com
In health, haemostasis and angiogenesis are tightly regulated processes, but may become
deregulated in cancer. Recent evidence suggests that platelet activation may link these …
deregulated in cancer. Recent evidence suggests that platelet activation may link these …
[HTML][HTML] Increased levels of NF-kB-dependent markers in cancer-associated deep venous thrombosis
G Malaponte, SS Signorelli, V Bevelacqua, J Polesel… - PLoS one, 2015 - journals.plos.org
Several studies highlight the role of inflammatory markers in thrombosis as well as in cancer.
However, their combined role in cancer-associated deep vein thrombosis (DVT) and the …
However, their combined role in cancer-associated deep vein thrombosis (DVT) and the …
Combined VEGF-A and VEGFR-2 concentrations in plasma: diagnostic and prognostic implications in patients with advanced NSCLC
INTRODUCTION: The vascular endothelial growth factor (VEGF) family of ligands and
receptors (VEGFR) play an important role in tumor angiogenesis. Increased expression of …
receptors (VEGFR) play an important role in tumor angiogenesis. Increased expression of …
Soluble CD40 ligand plasma levels in lung cancer
M Roselli, TC Mineo, S Basili, F Martini, S Mariotti… - Clinical cancer …, 2004 - AACR
Purpose: Tumor-induced platelet activation may cause the release of various cytokines,
including CD40 ligand (CD40L). Activation of the CD40/CD40L pathway in human tumors …
including CD40 ligand (CD40L). Activation of the CD40/CD40L pathway in human tumors …
[HTML][HTML] Systematic review of peri-operative prognostic biomarkers in pancreatic ductal adenocarcinoma
Background Pancreatic ductal adenocarcinoma (PDAC) continues to be associated with a
poor prognosis. This systematic review aimed to summarize the literature regarding potential …
poor prognosis. This systematic review aimed to summarize the literature regarding potential …