Neonatal opioid toxicity: Opioid withdrawal (abstinence) syndrome with emphasis on pharmacogenomics and respiratory depression

BA Baldo - Archives of Toxicology, 2023 - Springer
The increasing use of opioids in pregnant women has led to an alarming rise in the number
of cases of neonates with drug-induced withdrawal symptoms known as neonatal opioid …

Potential problems and solutions of opioid-based treatment in neonatal opioid withdrawal syndrome (NOWS): a scoping review protocol

S Mills-Huffnagle, JE Nyland - BMJ open, 2023 - bmjopen.bmj.com
Introduction Rates of neonatal opioid withdrawal syndrome (NOWS) have paralleled the rise
of opioid use during pregnancy. While short-term phenotypic symptoms of NOWS are well …

Motion robust MR fingerprinting scan to image neonates with prenatal opioid exposure

D Ma, C Badve, JEP Sun, S Hu, X Wang… - Journal of Magnetic …, 2024 - Wiley Online Library
Purpose To explore whether MR fingerprinting (MRF) scans provide motion‐robust and
quantitative brain tissue measurements for non‐sedated infants with prenatal opioid …

Neonatal withdrawal syndrome following in utero exposure to antidepressants: a disproportionality analysis of VigiBase, the WHO spontaneous reporting database

C Gastaldon, E Arzenton, E Raschi, O Spigset… - Psychological …, 2023 - cambridge.org
BackgroundEvidence on neonatal withdrawal syndrome following antidepressant
intrauterine exposure is limited, particularly for antidepressants other than selective …

Buprenorphine vs. morphine: impact on neonatal opioid withdrawal syndrome (NOWS) outcomes in a single center retrospective study

S Anbalagan, V Anderson, MT Favara, D Stark… - Journal of …, 2024 - nature.com
Objectives To compare clinical outcomes for infants with neonatal opioid withdrawal
syndrome (NOWS) treated with buprenorphine or morphine. Study design Retrospective …

Buprenorphine reduces somatic withdrawal in a mouse model of early-life morphine exposure

G Lepore, T Morley-McLaughlin, N Davidson… - Drug and Alcohol …, 2023 - Elsevier
The rising prevalence of early-life opioid exposure has become a pressing public health
issue in the US Neonates exposed to opioids in utero are at risk of experiencing a …

Multimodal Acute Pain Management in the Parturient with Opioid Use Disorder: A Review

V Koltenyuk, I Mrad, I Choe, MI Ayoub… - Journal of Pain …, 2024 - Taylor & Francis
The opioid epidemic in the United States has led to an increasing number of pregnant
patients with opioid use disorder (OUD) presenting to obstetric units. Caring for this complex …

Trends in maternal opioid use: Statewide differences by sociodemographic characteristics in Florida from 2000 to 2019

AL Elmore, NS Boghossian, AC McLain… - Journal of Addictive …, 2024 - Taylor & Francis
Background Maternal opioid use (MOU) remains a public health concern. Studies have
demonstrated significant increases in MOU, but estimates using ICD-10-CM or stratified by …

Optimizing a therapy for opiate use disorders: Characterizing ondansetron pharmacokinetics in blood and brain

M Wu, Z Cheng, AT Le, Y Tan… - Clinical and Translational …, 2023 - Wiley Online Library
Administration of a widely used 5‐hydroxytryptamine receptor (5HT3AR) antagonist
(ondansetron) potently inhibited the development of experimentally induced opioid …

Addicted to addictions: Why recovering from one deleterious habit may lead to the next

JL Maron - Clinical Therapeutics, 2023 - clinicaltherapeutics.com
This month, Clinical Therapeutics tackles alcohol use disorders, along with their treatments
and integrated, comprehensive therapies. Authors in this Special Topic Update highlight that …