In the past decade, multicomponent reactions have experienced a renaissance as powerful
peptide macrocyclization tools enabling the rapid creation of skeletal complexity and …

Small-ring heterocycles have found many applications both as useful starting materials in
the synthesis of more elaborate structures and as valuable targets of synthesis. Our review …

Isocyanide-based multicomponent reactions in the synthesis of heterocycles - RSC Advances
(RSC Publishing) DOI:10.1039/C6RA02143C Royal Society of Chemistry View PDF …

More than a decade ago, the question was raised by Sweeney if aziridines are epoxides'
ugly cousins? 1 The overview on the biological properties, synthetic accessibility, and useful …

Pseudaminic acid (Pse) is a nonulosonic acid unique to bacterial species, found as a
component of important cell surface glycans and glycoproteins in various pathogenic …

Conspectus Researchers continue to develop chemoselective synthesis strategies with the
goal of rapidly assembling complex molecules. As one appealing approach, chemists are …

Entry to bioactive boropeptides: MIDA‐containing α‐boryl isocyanides are isolable
molecules which allow one‐step access to boroalkyl‐functionalized heterocycles as well as …

Isocyanides were formally discovered by Gautier1 and Hofmann2 in 1867 but the history of
isocyanide chemistry in fact predates this discovery. Lieke carried out the first isocyanide …

The catalytic Mannich reaction of α-substituted α-isocyanoacetates with ketimines has been
investigated. A variety of imidazolines containing congested vicinal tetra-substituted …

By utilizing amino allenes, aldehydes, and aryl iodides as readily available building blocks,
a simple and modular synthesis of multisubstituted pyridines with flexible control over the …