From microbiome composition to functional engineering, one step at a time

SD Burz, S Causevic, A Dal Co… - Microbiology and …, 2023 - Am Soc Microbiol
Communities of microorganisms (microbiota) are present in all habitats on Earth and are
relevant for agriculture, health, and climate. Deciphering the mechanisms that determine …

<? mode longmeta?> SPIRE: a Searchable, Planetary-scale mIcrobiome REsource

TSB Schmidt, A Fullam, P Ferretti, A Orakov… - Nucleic Acids …, 2024 - academic.oup.com
Meta'omic data on microbial diversity and function accrue exponentially in public
repositories, but derived information is often siloed according to data type, study or sampled …

Removal of false positives in metagenomics-based taxonomy profiling via targeting Type IIB restriction sites

Z Sun, J Liu, M Zhang, T Wang, S Huang… - Nature …, 2023 - nature.com
Accurate species identification and abundance estimation are critical for the interpretation of
whole metagenome sequencing (WMS) data. Yet, existing metagenomic profilers suffer from …

Rapid species-level metagenome profiling and containment estimation with sylph

J Shaw, YW Yu - Nature Biotechnology, 2024 - nature.com
Profiling metagenomes against databases allows for the detection and quantification of
microorganisms, even at low abundances where assembly is not possible. We introduce …

[HTML][HTML] A cryptic plasmid is among the most numerous genetic elements in the human gut

EC Fogarty, MS Schechter, K Lolans, ML Sheahan… - Cell, 2024 - cell.com
Plasmids are extrachromosomal genetic elements that often encode fitness-enhancing
features. However, many bacteria carry" cryptic" plasmids that do not confer clear beneficial …

KMCP: accurate metagenomic profiling of both prokaryotic and viral populations by pseudo-mapping

W Shen, H Xiang, T Huang, H Tang, M Peng… - …, 2023 - academic.oup.com
Motivation The growing number of microbial reference genomes enables the improvement
of metagenomic profiling accuracy but also imposes greater requirements on the indexing …

Narrow host range phages infect essential bacteria for water purification reactions in groundwater-fed rapid sand filters

A Palomo, A Dechesne, BF Smets, Y Zheng - Water Research, 2023 - Elsevier
Biofiltration is used worldwide to provide safe potable water due to its low energy demand
and excellent treatment performance. For instance, in Denmark, over 95% of drinking water …

Surface microlayer-mediated virome dissemination in the Central Arctic

J Rahlff, G Westmeijer, J Weissenbach, A Antson… - Microbiome, 2024 - Springer
Background Aquatic viruses act as key players in shaping microbial communities. In polar
environments, they face significant challenges such as limited host availability and harsh …

the NEREa augmented Observatory: an integrative approach to marine coastal ecology

L Campese, L Russo, M Abagnale, A Alberti, G Bachi… - Scientific Data, 2024 - nature.com
Abstract The NEREA (Naples Ecological REsearch for Augmented observatories) initiative
aims to establish an augmented observatory in the Gulf of Naples (GoN), designed to …

Planning and Analyzing a Low-Biomass Microbiome Study: A Data Analysis Perspective

GI Austin, T Korem - The Journal of Infectious Diseases, 2024 - academic.oup.com
As investigations of low-biomass microbial communities have become more common, so too
has the recognition of major challenges affecting these analyses. These challenges have …