Liposomal nanomedicines
DB Fenske, PR Cullis - Expert opinion on drug delivery, 2008 - Taylor & Francis
Liposomal nanoparticles (LNs) encapsulating therapeutic agents, or liposomal
nanomedicines, represent an advanced class of drug delivery systems, with several …
nanomedicines, represent an advanced class of drug delivery systems, with several …
Ecology and evolution as targets: the need for novel eco-evo drugs and strategies to fight antibiotic resistance
In recent years, the explosive spread of antibiotic resistance determinants among
pathogenic, commensal, and environmental bacteria has reached a global dimension …
pathogenic, commensal, and environmental bacteria has reached a global dimension …
Formulation and delivery of siRNA by oleic acid and stearic acid modified polyethylenimine
A Alshamsan, A Haddadi, V Incani… - Molecular …, 2009 - ACS Publications
This study was conducted to formulate a nonviral delivery system for the delivery of small
interfering RNA (siRNA) to B16 melanoma cells in vitro. For this purpose, oleic and stearic …
interfering RNA (siRNA) to B16 melanoma cells in vitro. For this purpose, oleic and stearic …
Designing an effective therapeutic siRNA to silence RdRp gene of SARS-CoV-2
The devastating outbreak of COVID-19 has spread all over the world and has become a
global health concern. There is no specific therapeutics to encounter the COVID-19. Small …
global health concern. There is no specific therapeutics to encounter the COVID-19. Small …
MRNA therapy for Fabry disease
BC Guild, F DeRosa, M Heartlein - US Patent 9,308,281, 2016 - Google Patents
US9308281B2 - MRNA therapy for Fabry disease - Google Patents US9308281B2 - MRNA
therapy for Fabry disease - Google Patents MRNA therapy for Fabry disease Download PDF …
therapy for Fabry disease - Google Patents MRNA therapy for Fabry disease Download PDF …
siRNA and RNAi optimization
A Alagia, R Eritja - Wiley Interdisciplinary Reviews: RNA, 2016 - Wiley Online Library
The discovery and examination of the posttranscriptional gene regulatory mechanism known
as RNA interference (RNAi) contributed to the identification of small interfering RNA (siRNA) …
as RNA interference (RNAi) contributed to the identification of small interfering RNA (siRNA) …
MRNA therapy for phenylketonuria
F DeRosa, M Heartlein, A Dias - US Patent 9,522,176, 2016 - Google Patents
3,096.560 A 7, 1963 Liebig(PAH) at an effective dose and an administration interval
3,535,289 A 10, 1970 Yoshihara et al. such that at least one symptom or feature of PKU is …
3,535,289 A 10, 1970 Yoshihara et al. such that at least one symptom or feature of PKU is …
Therapeutic uses of inhibitors of RTP801
E Feinstein, J Kaufmann, K Giese - US Patent 7,741,299, 2010 - Google Patents
JLCPHMBAVCMARE-UHFFFAOYSA-N [3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-
oxo-1H-purin-9-yl)-3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[5-(2-amino-6-oxo …
oxo-1H-purin-9-yl)-3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[5-(2-amino-6-oxo …
Pulmonary delivery of mRNA
BC Guild, F DeRosa, M Heartlein - US Patent 9,597,413, 2017 - Google Patents
US9597413B2 - Pulmonary delivery of mRNA - Google Patents US9597413B2 - Pulmonary
delivery of mRNA - Google Patents Pulmonary delivery of mRNA Download PDF Info Publication …
delivery of mRNA - Google Patents Pulmonary delivery of mRNA Download PDF Info Publication …
Cftr mrna compositions and related methods and uses
M Heartlein, BC Guild, F DeRosa, C Rudolph… - US Patent …, 2015 - Google Patents
First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
50513499&utm_source= google_patent&utm_medium= platform_link&utm_campaign …
50513499&utm_source= google_patent&utm_medium= platform_link&utm_campaign …