Application and outlook of electrochemical technology in single-cell analysis

K Huang, YH Wang, H Zhang, TY Wang, XH Liu… - Biosensors and …, 2023 - Elsevier
Cellular heterogeneity, especially in some important diseased cells like tumor cells, acts as
an invisible driver for disease development like cancer progression in the tumor ecosystem …

Unlocking the electrochemical functions of biomolecular condensates

Y Dai, ZG Wang, RN Zare - Nature Chemical Biology, 2024 - nature.com
Biomolecular condensation is a key mechanism for organizing cellular processes in a
spatiotemporal manner. The phase-transition nature of this process defines a density …

Interface of biomolecular condensates modulates redox reactions

Y Dai, CF Chamberlayne, MS Messina, CJ Chang… - Chem, 2023 - cell.com
Biomolecular condensates mediate diverse cellular processes. The density-transition
process of condensate formation results in the selective partitioning of molecules, which …

Hydrogen bond organic frameworks as radical reactors for enhancement in ECL efficiency and their ultrasensitive biosensing

KY Shen, J Zhan, L Shen, Z Xiong, HT Zhu… - Analytical …, 2023 - ACS Publications
Nowadays, electrochemiluminescence (ECL) efficiency of an organic emitter is closely
related with its potential applications in food safety and environmental monitoring fields. In …

Emerging Data Processing Methods for Single‐Entity Electrochemistry

X Li, YH Fu, N Wei, RJ Yu, H Bhatti, L Zhang… - Angewandte …, 2024 - Wiley Online Library
Single‐entity electrochemistry is a powerful tool that enables the study of electrochemical
processes at interfaces and provides insights into the intrinsic chemical and structural …

A little less aggregation a little more replication: Viral manipulation of stress granules

MJ Brownsword, N Locker - Wiley Interdisciplinary Reviews …, 2023 - Wiley Online Library
Recent exciting studies have uncovered how membrane‐less organelles, also known as
biocondensates, are providing cells with rapid response pathways, allowing them to re …

Hepatocyte DDX3X protects against drug-induced acute liver injury via controlling stress granule formation and oxidative stress

T Luo, S Yang, T Zhao, H Zhu, C Chen, X Shi… - Cell Death & …, 2023 - nature.com
Drug-induced liver injury (DILI) is the leading cause of acute liver failure (ALF). Continuous
and prolonged hepatic cellular oxidative stress and liver inflammatory stimuli are key …

Detection of bacterial rhamnolipid toxin by redox liposome single impact electrochemistry

J Luy, D Ameline, C Thobie‐Gautier… - Angewandte …, 2022 - Wiley Online Library
The detection of Rhamnolipid virulence factor produced by Pseudomonas aeruginosa
involved in nosocomial infections is reported by using the redox liposome single impact …

Progress and limitations in reactive oxygen species quantitation

EM Spanolios, RE Lewis, RN Caldwell… - Chemical …, 2024 - pubs.rsc.org
Reactive oxygen species (ROS) are a set of oxygen-and nitrogen-containing radicals. They
are produced from a wide range of sources. In biological contexts, cellular stress leads to an …

Charge Asymmetry Suppresses Coarsening Dynamics in Polyelectrolyte Complex Coacervation

S Chen, ZG Wang - Physical Review Letters, 2023 - APS
Mixing solutions of oppositely charged macromolecules can result in liquid-liquid phase
separation into a polymer-rich coacervate phase and a polymer-poor supernatant phase …