pathfindR: an R package for comprehensive identification of enriched pathways in omics data through active subnetworks

E Ulgen, O Ozisik, OU Sezerman - Frontiers in genetics, 2019 - frontiersin.org
Pathway analysis is often the first choice for studying the mechanisms underlying a
phenotype. However, conventional methods for pathway analysis do not take into account …

A multi-objective genetic algorithm to find active modules in multiplex biological networks

EM Novoa-del-Toro, E Mezura-Montes… - PLoS computational …, 2021 - journals.plos.org
The identification of subnetworks of interest—or active modules—by integrating biological
networks with molecular profiles is a key resource to inform on the processes perturbed in …

A scenario-based genetic algorithm for controlling supercapacitor aging and degradation in the industry 4.0 era

IA Khan, M Khaleghiabbasabadi, D Silvestri… - … Applications of Artificial …, 2024 - Elsevier
Electric double layer capacitors (EDLCs) are promising energy storage solutions, yet aging
and degradation issues impede reliability and lifespan. The research proposes integrated …

pathfindR: an R package for pathway enrichment analysis utilizing active subnetworks

E Ulgen, O Ozisik, OU Sezerman - BioRxiv, 2018 - biorxiv.org
PathfindR is a tool for pathway enrichment analysis utilizing active subnetworks. It identifies
gene sets that form active subnetworks in a protein-protein interaction network using a list of …

Comparison of Disease Specific Sub-Network Identification Programs

B Adanur, BB Gungor - 2018 3rd International Conference on …, 2018 - ieeexplore.ieee.org
Active sub-network search aims to identify a group of interconnected genes in a protein-
protein interaction network that contains most of the disease-associated genes. In recent …

A comparative study on psychiatric disorders: Identification of shared pathways and common agents

C Kuzudİşlİ, BB Güngör - 2022 Innovations in Intelligent …, 2022 - ieeexplore.ieee.org
Distinct but closely related diseases generally present shared symptoms, which address
possible overlaps among their pathogenic mechanisms. Identification of significantly …

prePathCluster: An novel deep-learning based method for endocrine disease pathway analysis

N Zhang, T Zang - 2021 IEEE International Conference on …, 2021 - ieeexplore.ieee.org
Identification and investigation of molecular pathways are important in exploring the
underlying mechanism of complex diseases. With the help of molecular and intermolecular …

Evaluation of Sub-Network search programs in epilepsy-related GWAS dataset

B Bakir Gungor, B Adanur Dedetürk - 2022 - openaccess.agu.edu.tr
The active sub-network detection aims to find a group of interconnected genes of disease-
related genes in a protein-protein interaction network. In recent years, several algorithms …

Using Genetic Algorithm to Extract an Active Subnetwork

N Karimli - 2022 - search.proquest.com
Son yıllarda, biyoinformatik alanında, hastalıkların davranışlarını anlamak ve hastalıkların
tedavisinde kullanılabilecek ilaçların bulunabilmesi için genlerin analizi ve büyük protein …

Evaluation of Sub-Network search programs in epilepsy-related GWAS dataset

BA Dedeturk, BB Gungor - Pamukkale Üniversitesi Mühendislik …, 2022 - dergipark.org.tr
The active sub-network detection aims to find a group of interconnected genes of disease-
related genes in a protein-protein interaction network. In recent years, several algorithms …