Many Leishmania antigens have been identified as members of conserved protein families,
such as the acidic ribosomal proteins, the histones and the heat-shock proteins; despite this …

Publisher Summary This chapter reviews the structural and functional properties of different
eukaryotic stalk components, focusing on the Saccharomyces cerevisiae system for which …

Background Leishmania and other intracellular pathogens have evolved strategies that
support invasion and persistence within host target cells. In some cases the underlying …

Leishmania are evolutionarily ancient protozoans (Kinetoplastidae) and important human
pathogens that cause a spectrum of diseases ranging from the asymptomatic to the lethal …

Protein P0 in Saccharomyces cerevisiae is found only in the ribosomes and not free in a
cytoplasmic pool like the structurally related acidic P1 and P2 proteins. Analogously, P0 …

Background The factors influencing variation in the clinical forms of Chagas disease have
not been elucidated; however, it is likely that the genetics of both the host and the parasite …

Leishmania major is the main causative agent of cutaneous leishmaniasis in humans. The
Friedlin strain of this species (LmjF) was chosen when a multi-laboratory consortium …

The parasitic protozoan Leishmania is the aetiological agent of a spectrum of clinical
diseases, ranging from disfiguring skin lesions to life-threatening visceral infection, and is a …

Introduction 3. Chromosomal organization and gene transcription 4. Copy number of genes
and regulation of gene expression 5. Regulation of mRNA processing 6. Regulation of …

Leishmania donovani is a unicellular parasite that causes visceral leishmaniasis, a fatal
disease in humans. In this study, a complete assembly of the genome of L. donovani is …