Obesity is accompanied by the activation of low-grade inflammatory activity in metabolically
relevant tissues. Studies have shown that obesity-associated insulin resistance results from …

Alzheimer's disease (AD), the most common form of dementia in late life, will become even
more prevalent by midcentury, constituting a major global health concern with huge …

This study was aimed at determining potential effects of apple-derived pectin on weight gain,
gut microbiota, gut barrier and metabolic endotoxemia in rat models of diet-induced obesity …

The consumption of W estern diets, high in sugar and saturated fat, is a crucial contributor to
the alarming incidence of obesity and its associated morbidities. These diets have been …

Socioeconomic and demographic transformations are occurring very rapidly in some areas
of the world, especially in South America, and are accompanied by changes in lifestyle …

The ingestion of excessive amounts of saturated fatty acids (SFAs) and transfatty acids
(TFAs) is considered to be a risk factor for cardiovascular diseases, insulin resistance …

Alzheimer's disease (AD) is associated with peripheral metabolic disorders. Clinical/
epidemiological data indicate increased risk of diabetes in AD patients. Here, we show that …

Hyperglycemia-induced inflammation and apoptosis have important roles in the
pathogenesis of diabetic cardiomyopathy. We recently found that a novel curcumin …

Western diets are characterized by both dietary omega-3 fatty acid deficiency and increased
fructose intake. The latter found in high amounts in added sugars such as sucrose and high …

Metabolic syndrome, a network of medical disorders that greatly increase the risk for
developing metabolic and cardiovascular diseases, has reached epidemic levels in many …