Lung cancer (LC) is one of the leading causes of cancer occurrence and mortality
worldwide. Treatment of patients with advanced and metastatic LC presents a significant …

Purpose The therapeutic efficacy of conventional chemotherapy against several solid tumors
is generally limited and this is often due to the development of resistance or poor delivery of …

This study was aimed at developing a nanoparticle strategy to overcome acquired
resistance against erlotinib in non-small cell lung cancer (NSCLC). To load erlotinib on …

Core–shell type lipid–polymer hybrid nanoparticles (CSLPHNPs) have emerged as a
multifunctional drug delivery platform. The delivery system combines mechanical …

The present work was developed the pH dependent-aptamer AS1411 (APT) decorated and
erlotinib (En) loaded chitosan nanoparticles (CSNPs) for promising non-small-cell lung …

Engineered gold nanoparticles (AuNPs) find application in several fields related to human
activities (ie, food and cosmetic industry or water purification) including medicine, where …

In this study, detailed considerations of the interactions appearing at drug/metal nanoparticle
interfaces in micro-and nanoscale were performed. Application of the well-known surface …

Competitive reactions, on the surface of plasmonic nanostructures, allow exploiting SERS
signals for quantitative Therapeutic Drug Monitoring. As an example, the concentration of …

Tyrosine Kinases are enzymes that catalyse the phosphorylation of the tyrosine residues of
their substrates and activate downstream pathways involved in cellular proliferation. Their …

Gefitinib (GF) is a US Food and Drug Administration-approved epidermal growth factor
receptor (EGFR)-tyrosine kinase inhibitor for treating the lung cancers. We fabricated …